Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | NPC1 | O15118 | 9/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452865 | 1.00 | RAB9A (0.39) | RAB9ANPC1PKMFFAR2SMN1; SMN2 | |
| SCHEMBL4462546 | 0.83 | ALOX5 (0.51) | RAB9ANPC1PKMSMN1; SMN2POLB | |
| SCHEMBL4451612 | 0.82 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL4451603 | 0.82 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL4455208 | 0.79 | RAB9A (0.43) | RAB9ANPC1PKMFFAR2SMN1; SMN2 | |
| SCHEMBL4455204 | 0.79 | RAB9A (0.43) | RAB9ANPC1PKMFFAR2SMN1; SMN2 | |
| SCHEMBL4466274 | 0.75 | KIF11 (0.45) | RAB9ANPC1PKMALDH1A1MAPK1 | |
| SCHEMBL4466264 | 0.75 | KIF11 (0.45) | RAB9ANPC1PKMALDH1A1MAPK1 | |
| SCHEMBL4469973 | 0.74 | TSHR (0.44) | RAB9ANPC1PKMSMN1; SMN2POLB | |
| SCHEMBL4453343 | 0.74 | CSNK1D (0.50) | RAB9ANPC1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | claimed |
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |