Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79086 | 0.82 | HDAC3 (0.61) | KMT2AHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4328141 | 0.78 | KMT2A (0.53) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4459730 | 0.77 | MPO (0.55) | KMT2AMPOHDAC1HDAC2HDAC8 | |
| SCHEMBL25258141 | 0.76 | MKNK1 (0.49) | MPOHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30510166 | 0.76 | MKNK1 (0.49) | MPOHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7494123 | 0.76 | RAB9A (0.68) | KMT2AMPOHDAC1HDAC2HDAC8 | |
| SCHEMBL25252926 | 0.74 | MAPT (0.59) | KMT2AMPOHDAC1HDAC2HDAC8 | |
| SCHEMBL25380503 | 0.73 | GPR55 (0.50) | KMT2AHDAC1HDAC7NPC1RAB9A | |
| SCHEMBL25302168 | 0.73 | NPC1 (0.46) | MPOHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL30510191 | 0.73 | NPC1 (0.46) | MPOHDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009090548-A2 | 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-07-23 | — | — | WO | disclosed |