SCHEMBL4452418

SCHEMBL4452418

Fc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)n1C1(c2ccccc2F)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 5/20 0.35
AKT2 P31751 5/20 0.35
MGAM O43451 1/20 0.34
GAA P10253 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
MBNL1 Q9NR56 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
MAP4K1 Q92918 1/20 0.33
DCTPP1 Q9H773 1/20 0.33
DPP4 P27487 1/20 0.33
DHODH Q02127 2/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17133349 0.87 BCHE (0.36) AKT1AKT2GAAALDH1A1MAPT
SCHEMBL1865434 0.85 FABP4 (0.35) AKT1AKT2GAAALDH1A1MAPT
SCHEMBL30358507 0.82 KDM4E (0.38) ADORA2AADORA1ALDH1A1MAPTDPP4
SCHEMBL309105 0.82 AKT1 (0.36) AKT1AKT2GAAADORA2AALDH1A1
SCHEMBL30343795 0.82 AKT1 (0.36) AKT1AKT2GAAADORA2AALDH1A1
SCHEMBL23524454 0.82 L3MBTL1 (0.45) ADORA1ALDH1A1MAPTMEN1NPC1
SCHEMBL307900 0.81 MAPK1 (0.34) AKT1AKT2ALDH1A1MAPTBCHE
SCHEMBL29618231 0.81 MAPK1 (0.34) AKT1AKT2ALDH1A1MAPTBCHE
SCHEMBL29749791 0.81 HSD11B1 (0.37) AKT1AKT2GAAALDH1A1BCHE
SCHEMBL29359500 0.81 HSD11B1 (0.37) AKT1AKT2GAAALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569327-B2 Curable polymer compound SHOWDA DENKO K.K. (JP) 2009-08-04 US disclosed
EP-1629046-B1 CURABLE POLYMER COMPOUND SHOWA DENKO KK (JP) 2008-05-14 EP disclosed
US-20070083012-A1 Curable polymer compound SHOWA DENKO K.K. (JP) 2007-04-12 US disclosed
US-20070021571-A1 Curable polymer compound SHOWA DENKO K.K. (JP) 2007-01-25 US disclosed
US-20060041053-A1 Color filter black matrix resist composition and carbon black dispersion composition used for the composition SHOWA DENKO K.K. (JP) 2006-02-23 US disclosed