Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 6/20 | 0.33 |
| ▸ | MMP3 | P08254 | 6/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440561 | 0.79 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL443990 | 0.79 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL442618 | 0.79 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL6117766 | 0.79 | LMNA (0.42) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL23903262 | 0.78 | MEN1 (0.34) | — | |
| SCHEMBL439287 | 0.78 | ACE2 (0.46) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL442233 | 0.78 | ACE2 (0.46) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL440272 | 0.78 | LMNA (0.41) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL442232 | 0.78 | LMNA (0.37) | LCKPPARDZDHHC20ZDHHC2THRA | |
| SCHEMBL804973 | 0.77 | TGFBR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835368-B2 | Compounds and a method of lubricating an internal combustion engine | THE LUBRIZOL CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120065110-A1 | Compounds and a Method of Lubricating an Internal Combustion Engine | THE LUBRIZOL CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |