Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4450887 | 0.85 | ESR1 (0.46) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL4461680 | 0.84 | CYP2C9 (0.46) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL4450286 | 0.84 | AMY1A (0.44) | CYP2C9CYP2C19HIF1ASMN1; SMN2AMY1A | |
| SCHEMBL4463547 | 0.83 | AMY1A (0.46) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL4449573 | 0.81 | THRA (0.42) | CYP2C9CYP2C19HIF1ASMN1; SMN2AMY1A | |
| SCHEMBL4456786 | 0.81 | AMY1A (0.46) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL8772256 | 0.79 | HSPA5 (0.68) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL4463472 | 0.76 | NUDT1 (0.43) | AMY1ATHRATHRBHSP90AA1 | |
| SCHEMBL1417388 | 0.74 | AMY1A (0.45) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 | |
| SCHEMBL699786 | 0.74 | HSPA5 (0.51) | CYP2C9CYP2C19HIF1ASMN1; SMN2HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7586009-B2 | Bis-(hydroxybenzaldehyde) compound and novel polynuclear polyphenol compound derived therefrom and method for production thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20090076310-A1 | NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076310-A1 | NOVEL BIS-(HYDROXYBENZALDEHYDE) COMPOUND AND NOVEL POLYNUCLEAR POLYPHENOL COMPOUND DERIVED THEREFROM AND METHOD FOR PRODUCTION THEREOF | DDT, PAH, HPD | CYP2C9 1583/4885CYP2C19 1604/4885HIF1A 2768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.