SCHEMBL4452485

SCHEMBL4452485

C[CH]CCCC(C)CCCC(C)C

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
BLM P54132 1/20 0.45
PTPN1 P18031 3/20 0.44
MEN1 O00255 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 1/20 0.44
FNTA P49354 1/20 0.33
PGGT1B P53609 1/20 0.33
PTPN2 P17706 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9428032 1.00 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL56904 0.89
SCHEMBL27405080 0.87
SCHEMBL1417422 0.81
SCHEMBL8920757 0.81 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL9621895 0.81 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL10422397 0.81 LMNA (0.50) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL7094517 0.81 LMNA (0.39) LMNAMEN1CYP3A4ALOX15KMT2A
SCHEMBL20928 0.81 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL538230 0.81 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309913-B1 Fungicidal N-substituted 3-aryl-pyrrolidine derivatives BASF AG (DE) 1994-06-15 EP claimed
US-5068245-A For treatment of plants BASF AKTIENGESELLSCHAFT (DE) 1991-11-26 US claimed
EP-0309913-A2 Fungicidal N-substituted 3-aryl-pyrrolidine derivatives BASF Aktiengesellschaft (DE) 1989-04-05 EP claimed
CN-116685409-A Method for flotation of silicate-containing iron ore 巴斯夫欧洲公司 2023-09-01 CN disclosed
US-20210348081-A1 METHOD FOR RELEASING ALDEHYDE OR KETONE TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-11-11 US disclosed
WO-2021132214-A1 α-HYDROXYISOBUTYRIC ACID ESTER COMPOUND AND FRAGRANCE COMPOSITION 三菱瓦斯化学株式会社 2021-07-01 WO disclosed
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE KYOWA KIRIN CO., LTD. (JP) 2020-11-26 US disclosed
EP-3662913-A1 NUCLEIC-ACID-CONTAINING LIPID NANOPARTICLES Kyowa Kirin Co., Ltd. (JP) 2020-06-10 EP disclosed
EP-3572518-A1 METHOD FOR RELEASING ALDEHYDE OR KETONE Takasago International Corporation (JP) 2019-11-27 EP disclosed
US-20190338216-A1 METHOD FOR RELEASING ALDEHYDE OR KETONE TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-11-07 US disclosed
US-20180353434-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES KYOWA HAKKO KIRIN CO., LTD. (JP) 2018-12-13 US disclosed
EP-0309913-A2 Fungicidal N-substituted 3-aryl-pyrrolidine derivatives BASF Aktiengesellschaft (DE) 1989-04-05 EP disclosed
EP-0129211-B1 2,6-TRANS-DIMETHYL MORPHOLINE DERIVATIVES, FUNGICIDES CONTAINING THEM AND METHODS OF COMBATING FUNGI BASF Aktiengesellschaft (DE) 1987-02-04 EP disclosed
EP-0209763-A1 Salts of morpholiniocarboxylic esters and morpholinioalkyl-phenylethers, processes for their preparation, and their use as fungicides Institut für Pflanzenschutzforschung Kleinmachnow der A.d.L. der DDR (DD) 1987-01-28 EP disclosed
EP-0129211-A1 2,6-Trans-dimethyl morpholine derivatives, fungicides containing them and methods of combating fungi BASF Aktiengesellschaft (DE) 1984-12-27 EP disclosed
EP-0001809-B1 SYNERGETIC INSECTICIDAL AND ACARICIDAL MIXTURES BASF Aktiengesellschaft (DE) 1982-02-03 EP disclosed
EP-0003211-B1 PROCESS TO CONTROL PESTS WITH IMIDAZOLE DERIVATIVES BASF Aktiengesellschaft (DE) 1981-11-25 EP disclosed
US-4282238-A IMIDAZOLES BASF AKTIENGESELLSCHAFT (DE) 1981-08-04 US disclosed
EP-0003211-A1 Process to control pests with imidazole derivatives BASF Aktiengesellschaft (DE) 1979-08-08 EP disclosed
EP-0001809-A1 Synergetic insecticidal and acaricidal mixtures BASF Aktiengesellschaft (DE) 1979-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180353434-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES FASN, ABHD16A, PHAX LMNA 198/4885BLM 1466/4885PTPN1 3866/4885
US-20190338216-A1 METHOD FOR RELEASING ALDEHYDE OR KETONE APEH, AKR1C3, AKR7A2 LMNA 3555/4885BLM 4058/4885PTPN1 4838/4885
US-20210348081-A1 METHOD FOR RELEASING ALDEHYDE OR KETONE APEH, AKR7A2, FAAH2 LMNA 3203/4885BLM 3883/4885PTPN1 4859/4885
US-20200368173-A1 NUCLEIC ACID-CONTAINING LIPID NANOPARTICLE LIPA, LIPC, PNLIP LMNA 570/4885BLM 1471/4885PTPN1 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.