SCHEMBL4452573

SCHEMBL4452573

CCSc1[c]cccc1SCC

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.32
SOAT1 P35610 1/20 0.32
ALDH1A1 P00352 2/20 0.31
PKM P14618 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BCHE P06276 1/20 0.31
AOC3 Q16853 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30
NPC1 O15118 1/20 0.30
ATM Q13315 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498445 0.81 SCN1A (0.33) S100A4SOAT1LMNA
SCHEMBL2959533 0.79 MEN1 (0.32) S100A4SOAT1ALDH1A1KDM4E
SCHEMBL2974679 0.79 NOS3 (0.32) S100A4SOAT1
SCHEMBL2969614 0.79 LMNA (0.32) S100A4SOAT1NPC1LMNAHTT
SCHEMBL2970888 0.79 S100A4 (0.30) S100A4SOAT1
SCHEMBL15005130 0.79 PTGS2 (0.41) SOAT1ALDH1A1
SCHEMBL2969616 0.79 AOC3 (0.32) AOC3ADRA2AADRA2BADRA2CADRA1D
SCHEMBL2959535 0.79 ADRA2A (0.32) ADRA2AADRA2BADRA2CADRA1DADRA1A
SCHEMBL2974682 0.79 NPC1 (0.32) NPC1ATM
SCHEMBL2970889 0.79 ADRA2A (0.32) ALDH1A1PKMTDP1ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428202-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2019-01-16 EP claimed
US-20170267929-A1 DEVICE FOR REGULATING THE PASSAGE OF ENERGY MERCK PATENT GMBH (DE) 2017-09-21 US claimed
EP-3186334-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY Merck Patent GmbH (DE) 2017-07-05 EP claimed
WO-2016029996-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY MERCK PATENT GMBH (DE) 2016-03-03 WO claimed
EP-2984111-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2016-02-17 EP claimed
US-20140316085-A1 Process of Producing Polyolefins Using Metallocene Polymerization Catalysts and Copolymers Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US claimed
WO-2014169017-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-16 WO claimed
US-10370592-B2 Device for regulating the passage of energy MERCH PATENT GMBH (DE) 2019-08-06 US disclosed
EP-3428202-A1 PROCESS OF PRODUCING POLYOLEFINS USING METALLOCENE POLYMERIZATION CATALYSTS AND COPOLYMERS THEREFROM ExxonMobil Chemical Patents Inc. (US) 2019-01-16 EP disclosed
US-20170267929-A1 DEVICE FOR REGULATING THE PASSAGE OF ENERGY MERCK PATENT GMBH (DE) 2017-09-21 US disclosed
EP-3186334-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY Merck Patent GmbH (DE) 2017-07-05 EP disclosed
US-9611348-B2 Process of producing polyolefins using metallocene polymerization catalysts and copolymers therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-04-04 US disclosed
WO-2016029996-A1 DEVICE FOR CONTROLLING THE PASSAGE OF ENERGY MERCK PATENT GMBH (DE) 2016-03-03 WO disclosed
US-4401604-A Process for preparing thiosulfenamide derivatives of N-phosphonomethylglycine triesters MONSANTO COMPANY (US) 1983-08-30 US disclosed
US-4401455-A REACTING AN N-DIARYLPHOSPHONOMETHYL GLYCINE ESTER WITH AN ALKYL SULFENYL CHLORIDE; POSTEMERGENCE HERBICIDES MONSANTO COMPANY (US) 1983-08-30 US disclosed
US-4395374-A HERBICIDES, PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1983-07-26 US disclosed
US-4395276-A Thiosulfenamide derivatives of N-phosphonomethylglycinonitriles as herbicides MONSANTO COMPANY (US) 1983-07-26 US disclosed
EP-0055925-A2 Alkyl N-arylsulfenyl-N-diaryloxy-phosphinylmethylglycinates and their use as herbicides MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4300943-A Ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-11-17 US disclosed
US-4252554-A Herbicidal ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-02-24 US disclosed