Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 9/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.38 |
| ▸ | CPN1 | P15169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452815 | 1.00 | HSD11B1 (0.41) | HSD11B1DPP4CTSSLTA4HCPB2 | |
| SCHEMBL4450104 | 0.79 | CTSS (0.61) | CTSS | |
| SCHEMBL4450101 | 0.79 | CTSS (0.61) | CTSS | |
| SCHEMBL15203782 | 0.78 | CPN1 (0.48) | LTA4HCPB2CPN1 | |
| SCHEMBL8289702 | 0.78 | CTSS (0.59) | CTSS | |
| SCHEMBL2856572 | 0.77 | MMP2 (0.50) | LTA4HCPB2CPN1 | |
| SCHEMBL9208253 | 0.77 | MMP2 (0.50) | LTA4HCPB2CPN1 | |
| SCHEMBL31109109 | 0.77 | LTA4H (0.48) | LTA4HCPB2CPN1 | |
| SCHEMBL8871986 | 0.76 | CPN1 (0.50) | LTA4HCPB2CPN1 | |
| SCHEMBL4603755 | 0.75 | MMP2 (0.51) | LTA4HCPB2CPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | claimed |
| EP-1931359-A4 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS INC (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1931359-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | Elixir Pharmaceuticals, Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007033292-A2 | COMBINATION THERAPY FOR CONTROLLED CARBOHYDRATE DIGESTION | ELIXIR PHARMACEUTICALS, INC. (US) | 2007-03-22 | — | — | WO | disclosed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |