SCHEMBL4454491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1931317	0.79	ESR1 (0.50)	MAPTHTTHSD17B10GFERGPR55
	SCHEMBL1931315	0.79	ESR1 (0.50)	MAPTHTTHSD17B10GFERGPR55
	SCHEMBL2979315	0.78	CES2 (0.42)	MAPTHTTCA2MEN1KMT2A
	SCHEMBL28122546	0.78	RECQL (0.45)	MAPTCA2MEN1KMT2ALMNA
	SCHEMBL1055481	0.78	ALDH1A1 (0.42)	MAPTHTTHSD17B10MEN1KMT2A
	SCHEMBL28231639	0.78	MASP2 (0.41)	MAPTHSD17B10ESR1ESR2CA3
	SCHEMBL1094452	0.78	CES2 (0.42)	CA2MEN1KMT2ALMNACA1
	SCHEMBL11362763	0.78	CA2 (0.50)	MAPTCA12CA2CA3CA9
	SCHEMBL20882112	0.78	TDP1 (0.39)	MAPTMEN1KMT2ALMNANPC1
	SCHEMBL330617	0.77	ALDH1A1 (0.42)	MAPTMEN1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.