Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.50 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28277238 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGMNNPOLB | |
| SCHEMBL28480610 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAGMNNPOLB | |
| Sulfuric Acid SCHEMBL4454716 | 0.90 | LMNA (0.45) | ALDH1A1KDM4ELMNAGMNNPOLB | |
| SCHEMBL4281764 | 0.86 | LMNA (0.45) | ALDH1A1KDM4ELMNAGMNNPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL28355288 | 0.86 | LMNA (0.42) | ALDH1A1KDM4ELMNAGMNNPOLB | |
| Bicarbonate SCHEMBL27964415 | 0.86 | LMNA (0.54) | ALDH1A1KDM4ELMNAADRA2AADRA2C | |
| Methyl Alcohol SCHEMBL5316422 | 0.85 | ADRA2A (0.58) | ALDH1A1KDM4ELMNAADRA2AADRA2C | |
| SCHEMBL24932018 | 0.85 | DPP4 (0.58) | ALDH1A1KDM4ELMNAADRA2AADRA2C | |
| SCHEMBL830 | 0.85 | — | — | |
| SCHEMBL5565016 | 0.85 | DPP4 (0.58) | ALDH1A1KDM4ELMNAADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400556-B | Synthesis method of D- (-) -pantoic acid lactone | 上海应用技术大学 | 2022-12-09 | — | — | CN | claimed |
| CN-109400556-A | A kind of synthetic method of D- (-)-pantoic acid lactone | 上海应用技术大学 | 2019-03-01 | — | — | CN | claimed |
| CN-109400556-B | Synthesis method of D- (-) -pantoic acid lactone | 上海应用技术大学 | 2022-12-09 | — | — | CN | disclosed |
| CN-107074794-B | Method for producing polyvalent glycidyl compound | 昭和电工株式会社 | 2019-09-24 | — | — | CN | disclosed |
| CN-109400556-A | A kind of synthetic method of D- (-)-pantoic acid lactone | 上海应用技术大学 | 2019-03-01 | — | — | CN | disclosed |
| CN-107074794-A | Method for producing polyvalent glycidyl compound | 昭和电工株式会社 | 2017-08-18 | — | — | CN | disclosed |
| US-20090253932-A1 | Resolution of Racemic Organic Acids with (1S, 4S)-4[3,4-Dichlorophenyl]-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthaloneamine | MATRIX LABORATORIES LTD (IN) | 2009-10-08 | — | — | US | disclosed |
| EP-1831132-A2 | RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE | Matrix Laboratories Ltd (IN) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006013581-A2 | RESOLUTION OF RACEMIC ORGANIC ACIDS WITH (1S, 4S)-4[3,4-DICHLOROPHENYL]-1,2,3,4- TETRAHYDRO-N-METHYL-1-NAPHTHALONEAMINE | MATRIX LABORATORIES LTD (IN) | 2006-02-09 | — | — | WO | disclosed |
| US-3941814-A | Process for obtaining D(-)-and L(+)-α-azidophenylacetic acid | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253932-A1 | Resolution of Racemic Organic Acids with (1S, 4S)-4[3,4-Dichlorophenyl]-1,2,3,4-Tetrahydro-N-Methyl-1-Naphthaloneamine | HTR4, OXER1, CYP2S1 | ADRA2A 500/4885ADRA2C 196/4885ADRB2 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.