Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 16/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973238 | 0.91 | ATM (0.47) | ATMDHODHKMT2AEGFRSTIM1 | |
| SCHEMBL973104 | 0.81 | LMNA (0.56) | ATMDHODH | |
| SCHEMBL4477674 | 0.79 | CHRNA7 (0.42) | DHODHEGFR | |
| SCHEMBL3387363 | 0.79 | ATM (0.47) | ATMDHODHKMT2AEGFR | |
| SCHEMBL4455883 | 0.78 | LMNA (0.45) | ATMDHODH | |
| SCHEMBL28350646 | 0.77 | KMT2A (0.43) | DHODHKMT2AEGFRSTIM1ORAI1 | |
| SCHEMBL972255 | 0.77 | EGFR (0.48) | DHODHEGFR | |
| SCHEMBL2474435 | 0.76 | LMNA (0.46) | ATMDHODHEGFR | |
| SCHEMBL3685890 | 0.74 | HTT (0.43) | DHODHKMT2ASTIM1ORAI1 | |
| SCHEMBL31475430 | 0.74 | ATM (0.69) | ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100503577-C | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-06-24 | — | — | CN | disclosed |
| US-7521397-B2 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | disclosed |
| US-7329633-B2 | Disubstituted pyrazolylcarboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-17 | — | — | US | disclosed |
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-06-01 | — | — | US | disclosed |
| CN-1646494-A | Disubstituted pyrazolyl carboxanilides | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116414-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, RRS1, CBR3 | ATM 1894/4885DHODH 1446/4885KMT2A 2969/4885 |
| US-20080015244-A1 | Disubstituted pyrazolyl carboxanilides | MRPL21, CBR3, CBR1 | ATM 1622/4885DHODH 884/4885KMT2A 2905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.