Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10988348 | 0.79 | ALDH1A1 (0.44) | L3MBTL1LMNA | |
| SCHEMBL20166075 | 0.78 | L3MBTL1 (0.41) | L3MBTL1LMNA | |
| SCHEMBL13351506 | 0.78 | OPRM1 (0.70) | L3MBTL1PKMOPRM1MAOAMAOB | |
| Encyprate SCHEMBL122353 | 0.77 | L3MBTL1 (0.55) | L3MBTL1POLBLMNAOPRM1 | |
| SCHEMBL5987370 | 0.77 | ALOX5 (0.47) | L3MBTL1POLBPKMLMNAMAPT | |
| SCHEMBL10990804 | 0.77 | ALDH1A1 (0.40) | L3MBTL1LMNA | |
| SCHEMBL5689582 | 0.77 | CHRM5 (0.44) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27493502 | 0.77 | L3MBTL1 (0.53) | L3MBTL1SLC18A3OPRM1MAOAMAOB | |
| SCHEMBL13684267 | 0.76 | L3MBTL1 (0.63) | L3MBTL1 | |
| SCHEMBL31126845 | 0.76 | CYP1A2 (0.41) | L3MBTL1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622526-B2 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL (FR) | 2009-11-24 | — | — | US | disclosed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | disclosed |
| US-20060270771-A1 | Thermoset material based on antiplasticizing polythiourethane and ophthalmic lens comprising an antiplasticized thermoset material | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2006-11-30 | — | — | US | disclosed |