Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | NCF1 | P14598 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096843 | 0.98 | KDM4E (0.48) | KDM4EALDH1A1PLD1ADRB2NCF1 | |
| SCHEMBL1271673 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1PLD1ADRB2NCF1 | |
| SCHEMBL300491 | 0.81 | ALOX15 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL311710 | 0.79 | BCHE (0.42) | ALDH1A1HRH3 | |
| Hydrochloric Acid SCHEMBL9200760 | 0.79 | ALOX15 (0.39) | KDM4EALDH1A1HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL29375122 | 0.78 | BCHE (0.41) | KDM4EALDH1A1HRH3 | |
| SCHEMBL6840293 | 0.76 | NPC1 (0.41) | HTR3AHRH3HTR6 | |
| SCHEMBL6904489 | 0.76 | TP53 (0.45) | KDM4E | |
| SCHEMBL21047581 | 0.74 | HIPK2 (0.42) | ALDH1A1 | |
| SCHEMBL5891722 | 0.73 | HIPK2 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9334227-B2 | Carbonylation of ethylenically unsaturated compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2016-05-10 | — | — | US | disclosed |
| US-20090163724-A1 | Carbonylation of Ethylenically Unsaturated Compounds | LUCITE INTERNATIONAL UK LIMITED (GB) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163724-A1 | Carbonylation of Ethylenically Unsaturated Compounds | CBR3, ETFA, ACOX3 | KDM4E 1132/4885ALDH1A1 454/4885PLD1 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.