SCHEMBL445644

SCHEMBL445644

CC(C)(C)C(CN)OC(N)=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
TSHR P16473 3/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX15 P16050 1/20 0.32
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31
ADRA1A P35348 1/20 0.31
RAB9A P51151 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28712321 0.83 LMNA (0.35) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL5100758 0.83 GABRR1 (0.35) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL28418994 0.82 LMNA (0.38) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL1829129 0.82 LMNA (0.38) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL20416250 0.82 LMNA (0.41) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL28415266 0.82 LMNA (0.38) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL24623 0.80 LMNA (0.36) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL4966129 0.80 LMNA (0.36) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL2474842 0.80 LMNA (0.36) LMNATSHRCHRM2CHRM4CHRM5
SCHEMBL16330481 0.80 LMNA (0.36) LMNATSHRCHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
US-12595318-B2 2026-04-07 US disclosed
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
US-12479933-B2 Crosslinked alginic acid structure MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 US disclosed
US-20250223281-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2025-07-10 US disclosed
EP-3778653-B1 NOVEL REACTIVE ALGINIC ACID DERIVATIVES MOCHIDA PHARM CO LTD (JP) 2025-07-09 EP disclosed
EP-4406606-A2 ANTIBODY DRUG CONJUGATES (ADCS) AND ANTIBODY PRODRUG CONJUGATES (APDCS) WITH ENZYMATICALLY CLEAVABLE G Bayer Pharma Aktiengesellschaft (DE) 2024-07-31 EP disclosed
US-20240174772-A1 NOVEL CROSSLINKED ALGINIC ACID MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2024-05-30 US disclosed
US-11932708-B2 Crosslinked alginic acid MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2024-03-19 US disclosed
CN-111801322-B Kinase inhibitors for the treatment of central and peripheral nervous system disorders 迈阿密大学 2024-03-15 CN disclosed
US-20120277228-A1 Novel Azaheterocyclic Compounds MERCK PATENT GMBH (DE) 2012-11-01 US disclosed
EP-2462141-A1 NOVEL AZAHETEROCYCLIC COMPOUNDS Merck Patent GmbH (DE) 2012-06-13 EP disclosed
US-20120065202-A1 PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS CELLZOME LIMITED (GB) 2012-03-15 US disclosed
EP-2406258-A1 PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS Cellzome Limited (GB) 2012-01-18 EP disclosed
US-20110251547-A1 TRANSFECTION WITH MAGNETIC NANOPARTICLES AND ULTRASOUND INTELLIGENTNANO INC. (CA) 2011-10-13 US disclosed
WO-2011017009-A1 NOVEL AZAHETEROCYCLIC COMPOUNDS MERCK PATENT GMBH (DE) 2011-02-10 WO disclosed
WO-2010103094-A1 PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS CELLZOME LIMITED (GB) 2010-09-16 WO disclosed
EP-1856048-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS Theravance, Inc. (US) 2007-11-21 EP disclosed
WO-2006098999-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS THERAVANCE, INC. (US) 2006-09-21 WO disclosed
WO-2006099091-A1 BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS THERAVANCE, INC. (US) 2006-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 LMNA 696/4885TSHR 1079/4885CHRM2 893/4885
US-20120277228-A1 Novel Azaheterocyclic Compounds PCNA, MCL1, MYC LMNA 2699/4885TSHR 2685/4885CHRM2 4710/4885
US-20120065202-A1 PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS MTOR, RICTOR, RPTOR LMNA 2684/4885TSHR 2833/4885CHRM2 4135/4885
US-20250223281-A1 ANTIDIABETIC COMPOUNDS AND COMPOSITIONS GPR119, GLP1R, GPR65 LMNA 3812/4885TSHR 1353/4885CHRM2 422/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR LMNA 3318/4885TSHR 5/4885CHRM2 3020/4885
US-12595318-B2 ALG1, ALG8, FUCA1 LMNA 2167/4885TSHR 4227/4885CHRM2 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.