SCHEMBL4457019

SCHEMBL4457019

CCCCCCO[Si](CCCSSCCC[Si](OCCCCCC)(OCCCCCC)OCCCCCC)(OCCCCCC)OCCCCCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 6/20 0.35
LPAR2 Q9HBW0 5/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 2/20 0.32
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
CA1 P00915 7/20 0.31
CA2 P00918 7/20 0.31
CA9 Q16790 6/20 0.31
CA12 O43570 3/20 0.31
CA7 P43166 3/20 0.31
CA14 Q9ULX7 3/20 0.31
LPAR1 Q92633 2/20 0.31
CA3 P07451 2/20 0.31
CA4 P22748 2/20 0.31
CA6 P23280 2/20 0.31
CA5A P35218 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559157 1.00 LPAR3 (0.35) LPAR3LPAR2LMNATHRBMEN1
SCHEMBL5163532 0.92 LPAR2 (0.33) LPAR3LPAR2LMNATHRBMEN1
SCHEMBL209438 0.92 ADRB2 (0.32)
SCHEMBL11576860 0.91 LMNA (0.33) LPAR3LPAR2LMNA
SCHEMBL6663772 0.88 ADRB2 (0.30)
SCHEMBL23534202 0.88 LMNA (0.31) LPAR3LPAR2LMNA
SCHEMBL5165384 0.88 LMNA (0.31) LPAR3LPAR2LMNA
SCHEMBL5162494 0.88 LMNA (0.31) LPAR3LPAR2LMNA
SCHEMBL1196423 0.85
SCHEMBL9009725 0.85 LPAR3 (0.41) LPAR3LPAR2LMNATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240059800-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2024-02-22 US claimed
EP-4263567-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2023-10-25 EP claimed
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN claimed
WO-2022133477-A1 MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES BRIDGESTONE CORPORATION (JP) 2022-06-23 WO claimed
EP-2658910-A1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT Bridgestone Corporation (JP) 2013-11-06 EP claimed
WO-2012092062-A1 RUBBER COMPOSITION WITH IMPROVED BIS-SILANE REINFORCEMENT BRIDGESTONE CORPORATION (JP) 2012-07-05 WO claimed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP claimed
US-20060086450-A1 Method of producing a tire composition having improved silica reinforcement BRIDGESTONE CORPORATION 2006-04-27 US claimed
EP-1636307-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2006-03-22 EP claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
WO-2004106427-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2004-12-09 WO claimed
US-20250250424-A1 RUBBER COMPOSITION BASED ON MULTIPHASE DILUTION OF COMPOSITE BLEND THE GOODYEAR TIRE & RUBBER COMPANY 2025-08-07 US disclosed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
CN-117986694-A Precipitated silica pretreated with coupling agent and polyethylene glycol for rubber compositions 固特异轮胎和橡胶公司 2024-05-07 CN disclosed
EP-0794188-B1 Na, k and Li salts of siloxy compounds GOODYEAR TIRE & RUBBER (US) 2002-07-03 EP disclosed
US-6316567-B1 DURABILITY OF TIRE TREADS THE GOODYEAR TIRE & RUBBER COMPANY 2001-11-13 US disclosed
EP-0763558-B1 Heterogeneous silica carbon black-filled rubber compound GOODYEAR TIRE & RUBBER (US) 2001-03-21 EP disclosed
EP-0900821-A1 Method of improving the abrasion resistance of a rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-03-10 EP disclosed
US-5783640-A Rubber compositions containing a disodium salt of 2, 2'-dithiosalicyclic acid THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-07-21 US disclosed