SCHEMBL5163532

SCHEMBL5163532

CCCCCCCCO[Si](CCCSSSSCCC[Si](OCCCCCCCC)(OCCCCCCCC)OCCCCCCCC)(OCCCCCCCC)OCCCCCCCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LPAR2 Q9HBW0 3/20 0.33
LPAR3 Q9UBY5 3/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11576860 0.98 LMNA (0.33) LPAR2LPAR3LMNA
SCHEMBL23534202 0.95 LMNA (0.31) LPAR2LPAR3LMNA
SCHEMBL5162494 0.95 LMNA (0.31) LPAR2LPAR3LMNA
SCHEMBL5165384 0.95 LMNA (0.31) LPAR2LPAR3LMNA
SCHEMBL7559157 0.92 LPAR3 (0.35) LPAR2LPAR3LMNAMEN1THRB
SCHEMBL4457019 0.92 LPAR3 (0.35) LPAR2LPAR3LMNAMEN1THRB
SCHEMBL210260 0.92 ADRB2 (0.30)
SCHEMBL11575868 0.91
SCHEMBL14191181 0.89 ADRB2 (0.30)
SCHEMBL7609809 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN claimed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP claimed
EP-1448570-B1 PROCESS FOR PREPARING SILYLORGANOMERCAPTANS GEN ELECTRIC (US) 2007-03-28 EP claimed
EP-1636307-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2006-03-22 EP claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
WO-2004106427-A1 SILANE-MODIFIED PHENOLIC RESINS AND APPLICATIONS THEREOF INDSPEC CHEMICAL CORPORATION (US) 2004-12-09 WO claimed
EP-1448570-A1 PROCESS FOR PREPARING SILYLORGANOMERCAPTANS GENERAL ELECTRIC COMPANY (US) 2004-08-25 EP claimed
WO-2003040153-A1 PROCESS FOR PREPARING SILYLORGANOMERCAPTANS GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO claimed
US-6433206-B1 CLEAVAGE OF SULFUR-SULFUR BOND CROMPTON CORPORATION 2002-08-13 US claimed
EP-1208165-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG Industries Ohio, Inc. (US) 2002-05-29 EP claimed
EP-1208164-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG Industries Ohio Inc. (US) 2002-05-29 EP claimed
WO-2001021715-A1 PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-03-29 WO claimed
WO-2001012733-A1 PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO claimed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
CN-117986694-A Precipitated silica pretreated with coupling agent and polyethylene glycol for rubber compositions 固特异轮胎和橡胶公司 2024-05-07 CN disclosed
WO-2001012734-A1 CHEMICALLY MODIFIED FILLERS AND POLYMERIC COMPOSITIONS CONTAINING SAME PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO disclosed
WO-2001012732-A1 CHEMICALLY TREATED FILLERS AND POLYMERIC COMPOSITIONS CONTAINING SAME PPG INDUSTRIES OHIO, INC. (US) 2001-02-22 WO disclosed
US-5783640-A Rubber compositions containing a disodium salt of 2, 2'-dithiosalicyclic acid THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-07-21 US disclosed
US-4072701-A DI-, TRI-, AND TETRA-SULFIDES DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) 1978-02-07 US disclosed