Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 7/20 | 0.31 |
| ▸ | CA2 | P00918 | 7/20 | 0.31 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457019 | 1.00 | LPAR3 (0.35) | LPAR3LPAR2LMNATHRBMEN1 | |
| SCHEMBL5163532 | 0.92 | LPAR2 (0.33) | LPAR3LPAR2LMNATHRBMEN1 | |
| SCHEMBL209438 | 0.92 | ADRB2 (0.32) | — | |
| SCHEMBL11576860 | 0.91 | LMNA (0.33) | LPAR3LPAR2LMNA | |
| SCHEMBL6663772 | 0.88 | ADRB2 (0.30) | — | |
| SCHEMBL23534202 | 0.88 | LMNA (0.31) | LPAR3LPAR2LMNA | |
| SCHEMBL5165384 | 0.88 | LMNA (0.31) | LPAR3LPAR2LMNA | |
| SCHEMBL5162494 | 0.88 | LMNA (0.31) | LPAR3LPAR2LMNA | |
| SCHEMBL1196423 | 0.85 | — | — | |
| SCHEMBL9009725 | 0.85 | LPAR3 (0.41) | LPAR3LPAR2LMNATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403693-B2 | TIRES; ELASTOMER MATRIX | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-06-11 | — | — | US | disclosed |
| US-20020019473-A1 | SILICA REINFORCED RUBBER COMPOSITION AND USE IN TIRES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-14 | — | — | US | disclosed |