SCHEMBL5165384

SCHEMBL5165384

CCCCCCCCO[Si](CCCSSSSCCC[Si](OCC)(OCCCCCCCC)OCCCCCCCC)(OCC)OCCCCCCCC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5162494 1.00 LMNA (0.31) LMNALPAR2LPAR3
SCHEMBL23534202 1.00 LMNA (0.31) LMNALPAR2LPAR3
SCHEMBL5163532 0.95 LPAR2 (0.33) LMNALPAR2LPAR3
SCHEMBL11576860 0.93 LMNA (0.33) LMNALPAR2LPAR3
SCHEMBL7609809 0.93
Heptane SCHEMBL4013761 0.93 LMNA (0.34) LMNA
SCHEMBL28197962 0.90 ALDH1A1 (0.33) LMNA
SCHEMBL210260 0.88 ADRB2 (0.30)
SCHEMBL4457019 0.88 LPAR3 (0.35) LMNALPAR2LPAR3
SCHEMBL7559157 0.88 LPAR3 (0.35) LMNALPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448570-B1 PROCESS FOR PREPARING SILYLORGANOMERCAPTANS GEN ELECTRIC (US) 2007-03-28 EP claimed
US-6433206-B1 CLEAVAGE OF SULFUR-SULFUR BOND CROMPTON CORPORATION 2002-08-13 US claimed