SCHEMBL4457024

SCHEMBL4457024

CCCCCCO[Si](OCCCCCC)(OCCCCCC)C(CC)SS

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.32
USP2 O75604 1/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559164 1.00 DNM1 (0.32) DNM1USP2HTTMEN1THRB
SCHEMBL6551649 0.92 ADRB2 (0.30)
SCHEMBL504518 0.89 DNM1 (0.34) DNM1USP2HTTMEN1THRB
SCHEMBL6848627 0.89 DNM1 (0.34) DNM1USP2HTTMEN1THRB
SCHEMBL5669367 0.84
SCHEMBL8826511 0.81 DNM1 (0.32) DNM1USP2HTTMEN1THRB
SCHEMBL504637 0.81 DNM1 (0.32) DNM1USP2HTTMEN1THRB
SCHEMBL209439 0.80 ADRB2 (0.32)
SCHEMBL8826962 0.80 DNM1 (0.32) DNM1USP2
SCHEMBL8826579 0.80 DNM1 (0.32) DNM1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN claimed
US-20060086450-A1 Method of producing a tire composition having improved silica reinforcement BRIDGESTONE CORPORATION 2006-04-27 US claimed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
CN-117986694-A Precipitated silica pretreated with coupling agent and polyethylene glycol for rubber compositions 固特异轮胎和橡胶公司 2024-05-07 CN disclosed
WO-2023225398-A1 RUBBER FORMULATIONS YIELDING IMPROVED DYNAMIC PROPERTIES AND WEAR BRIDGESTONE CORPORATION (JP) 2023-11-23 WO disclosed
CN-113292772-B Accelerators for vulcanization of rubbery polymers 固特异轮胎和橡胶公司 2023-07-21 CN disclosed
CN-112608581-B Pneumatic tire 固特异轮胎和橡胶公司 2023-06-20 CN disclosed
CN-111479836-B Coupled polymer products, methods of manufacture, and compositions containing the same 株式会社普利司通 2023-05-23 CN disclosed
CN-113667194-B Pneumatic tire 固特异轮胎和橡胶公司 2023-05-12 CN disclosed
CN-111630075-B Functionalized polymer, process for preparing the functionalized polymer and rubber composition containing the functionalized polymer 株式会社普利司通 2023-04-28 CN disclosed
WO-2005105854-A2 METHOD OF PRODUCING A TIRE COMPOSITION HAVING IMPROVED SILICA REINFORCEMENT BRIDGESTONE CORPORATION (JP) 2005-11-10 WO disclosed
US-20050239946-A1 Preparation of tire composition having improved silica reinforcement BRIDGESTONE CORPORATION 2005-10-27 US disclosed
EP-0765904-B1 Sulfur vulcanizable rubber containing sodium thiosulfate pentahydrate GOODYEAR TIRE & RUBBER (US) 2003-11-12 EP disclosed
EP-1095974-B1 Rubber compositions containing a disodium salt of 3,3'-dithiodipropionic acid GOODYEAR TIRE & RUBBER (US) 2003-06-11 EP disclosed
EP-0949264-B1 Titanate compounds GOODYEAR TIRE & RUBBER (US) 2003-05-07 EP disclosed
US-6316567-B1 DURABILITY OF TIRE TREADS THE GOODYEAR TIRE & RUBBER COMPANY 2001-11-13 US disclosed
EP-0763558-B1 Heterogeneous silica carbon black-filled rubber compound GOODYEAR TIRE & RUBBER (US) 2001-03-21 EP disclosed
EP-0900821-A1 Method of improving the abrasion resistance of a rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-03-10 EP disclosed
US-5783640-A Rubber compositions containing a disodium salt of 2, 2'-dithiosalicyclic acid THE GOODYEAR TIRE & RUBBER COMPANY (US) 1998-07-21 US disclosed