Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826322 | 0.98 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826579 | 0.98 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826962 | 0.98 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826780 | 0.98 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826511 | 0.96 | DNM1 (0.32) | DNM1USP2HTTMEN1THRB | |
| SCHEMBL6848627 | 0.92 | DNM1 (0.34) | DNM1USP2HTTMEN1THRB | |
| SCHEMBL504518 | 0.92 | DNM1 (0.34) | DNM1USP2HTTMEN1THRB | |
| SCHEMBL209439 | 0.84 | ADRB2 (0.32) | — | |
| SCHEMBL7559164 | 0.81 | DNM1 (0.32) | DNM1USP2HTTMEN1THRB | |
| SCHEMBL4457024 | 0.81 | DNM1 (0.32) | DNM1USP2HTTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 763 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858821-B2 | Method of silica pretreatment | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-01-02 | — | — | US | claimed |
| EP-4023724-A2 | METHOD OF MAKING HYDROPHOBATED SILICA AND USE OF SUCH A SILICA | The Goodyear Tire & Rubber Company (US) | 2022-07-06 | — | — | EP | claimed |
| US-20220204351-A1 | METHOD OF SILICA PRETREATMENT | GOODYEAR TIRE & RUBBER COMPANY, THE | 2022-06-30 | — | — | US | claimed |
| US-7794782-B2 | Phosphonate and sulfido silane anti-corrosion additive for electrical cable restoration fluid | DOW CORNING CORPORATION (US) | 2010-09-14 | — | — | US | claimed |
| EP-1208165-B1 | PROCESS FOR PRODUCING CHEMICALLY MODIFIED FILLERS | PPG IND OHIO INC (US) | 2007-12-19 | — | — | EP | claimed |
| EP-1208164-B1 | PROCESS FOR PRODUCING CHEMICALLY TREATED FILLERS | PPG IND OHIO INC (US) | 2007-10-24 | — | — | EP | claimed |
| US-20070235700-A1 | Phosphonate and Sulfido Silane Anti-Corrosion Additve for Electrical Cable Restoration Fluid | DOW CORNING CORPORATION | 2007-10-11 | — | — | US | claimed |
| US-7259221-B2 | Silane-modified phenolic resins and applications thereof | INDSPEC CHEMICAL CORPORATION | 2007-08-21 | — | — | US | claimed |
| US-20050154151-A1 | Silane-modified phenolic resins and applications thereof | INDSPEC CHEMICAL CORPORATION | 2005-07-14 | — | — | US | claimed |
| US-6875807-B2 | Silane-modified phenolic resins and applications thereof | INDSPEC CHEMICAL CORPORATION (US) | 2005-04-05 | — | — | US | claimed |
| US-20030119995-A1 | Silica filler, coupling agent, cure-enhancing polyoxyalkylene oxide and high molecular weight thiuram disulfide; carbon black; ozone and oxidation resistance; tire treads | ADDIVANT USA, LLC | 2003-06-26 | — | — | US | claimed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | claimed |
| US-6390163-B1 | BUTADIENE OR ISOPRENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-05-21 | — | — | US | claimed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | claimed |
| US-6326424-B1 | BUTADIENE-ISOPRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-12-04 | — | — | US | claimed |
| US-6053226-A | BLENDING A DIENE BASED ELASTOMER, A REINFROCEMENT FILLER COMPRISED OF PRECIPITATED SILICA AND CARBON BLACK, A PREFORMED COMPOSITE OF MICROCRYSTALLINE WAX, SILICA COUPLING AGENT, ANTIDEGRADANT, VULCANIZATION PROMOTER AND CARBON BLACK | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-25 | — | — | US | claimed |
| EP-0764688-B1 | High performance blend for tire treads | GOODYEAR TIRE & RUBBER (US) | 2000-02-23 | — | — | EP | claimed |
| EP-0941872-A2 | Rubber composition reinforced with silica and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0764688-A1 | High performance blend for tire treads | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | claimed |
| US-5534592-A | POLYBUTADIENE RUBBER BLEND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | DNM1 3175/4885USP2 1533/4885HTT 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.