Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | CA1 | P00915 | 5/20 | 0.31 |
| ▸ | CA2 | P00918 | 5/20 | 0.31 |
| ▸ | CA9 | Q16790 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL504518 | 1.00 | DNM1 (0.34) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL8826511 | 0.92 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL504637 | 0.92 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL209439 | 0.92 | ADRB2 (0.32) | — | |
| SCHEMBL8826579 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826962 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826780 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826322 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL7559164 | 0.89 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL4457024 | 0.89 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384127-B2 | MIXTURE CONTAINING ORGANOSILANE DISULFIDE COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-05-07 | — | — | US | claimed |
| US-20020019473-A1 | SILICA REINFORCED RUBBER COMPOSITION AND USE IN TIRES | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-14 | — | — | US | claimed |
| US-20010034392-A1 | Preparation of reinforced rubber and use in tires | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-10-25 | — | — | US | claimed |
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | claimed |
| US-5675014-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | claimed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| US-5580919-A | ORGANOSILANE DISULFIDE COUPLER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-12-03 | — | — | US | claimed |
| US-6780925-B2 | ALKOXYSILANE AND/OR SULFUR CURE REACTIONS WITHIN THE ELASTOMER HOST ARE CONTROLLED BY THE USE OF A SELECTED AMINO ACID, OR AMINO ACID-CONTAINING PROTEIN BASED, ACTIVATOR. | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20030135006-A1 | Rubber composition with silica reinforcement obtained with an amino acid or amino acid-containing protein based activator and use thereof in tires | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-17 | — | — | US | disclosed |
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | disclosed |
| EP-1061097-A1 | Silica reinforced rubber composition and use in tires | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5684171-A | FROM DITHIODIMORPHOLINE AND A MERCAPTOSILANE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| US-5684172-A | REACTING BENZOTHIAZOLYL MORPHOLINYL DISULFIDE WITH A MERCAPTOALKYLALKOXYSILANE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-04 | — | — | US | disclosed |
| US-5675014-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0785207-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |