Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.31 |
| ▸ | CA1 | P00915 | 5/20 | 0.31 |
| ▸ | CA2 | P00918 | 5/20 | 0.31 |
| ▸ | CA9 | Q16790 | 5/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848627 | 1.00 | DNM1 (0.34) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL8826511 | 0.92 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL504637 | 0.92 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL209439 | 0.92 | ADRB2 (0.32) | — | |
| SCHEMBL8826579 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826962 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826780 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL8826322 | 0.91 | DNM1 (0.32) | DNM1USP2 | |
| SCHEMBL7559164 | 0.89 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 | |
| SCHEMBL4457024 | 0.89 | DNM1 (0.32) | DNM1THRBHTTUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240059800-A1 | MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES | BRIDGESTONE CORPORATION (JP) | 2024-02-22 | — | — | US | claimed |
| US-20240052139-A1 | TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS | BRIDGESTONE CORPORATION (JP) | 2024-02-15 | — | — | US | claimed |
| US-11858821-B2 | Method of silica pretreatment | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2024-01-02 | — | — | US | claimed |
| EP-4263621-A1 | TIRE RUBBER COMPOSITIONS COMBINING BAGASSE-CONTAINING GUAYULE RUBBER WITH SILANE AND RELATED METHODS | BRIDGESTONE CORPORATION (JP) | 2023-10-25 | — | — | EP | claimed |
| EP-4263567-A1 | MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES | BRIDGESTONE CORPORATION (JP) | 2023-10-25 | — | — | EP | claimed |
| US-20230129988-A1 | SILICA-FILLED RUBBER COMPOSITION AND METHOD FOR MAKING THE SAME | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC | 2023-04-27 | — | — | US | claimed |
| US-11535687-B2 | Silica-filled rubber composition and method for making the same | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2022-12-27 | — | — | US | claimed |
| EP-4023724-A2 | METHOD OF MAKING HYDROPHOBATED SILICA AND USE OF SUCH A SILICA | The Goodyear Tire & Rubber Company (US) | 2022-07-06 | — | — | EP | claimed |
| US-20220204351-A1 | METHOD OF SILICA PRETREATMENT | GOODYEAR TIRE & RUBBER COMPANY, THE | 2022-06-30 | — | — | US | claimed |
| WO-2022133477-A1 | MODIFIED GUAYULE RESIN PRODUCT AND RELATED PROCESSES | BRIDGESTONE CORPORATION (JP) | 2022-06-23 | — | — | WO | claimed |
| US-20030119960-A1 | Rubber compositions and method for decreasing the tangent delta value | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-26 | — | — | US | claimed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | claimed |
| US-6390163-B1 | BUTADIENE OR ISOPRENE-STYRENE COPOLYMER | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-05-21 | — | — | US | claimed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | claimed |
| WO-2002010271-A2 | PROPERTIES OF SILICA-FILLED RUBBER COMPOUNDS WITH DISULFANE SILICA COUPLING AGENTS AT HIGH MIXING TEMPERATURE | BRIDGESTONE CORPORATION (JP) | 2002-02-07 | — | — | WO | claimed |
| US-6053226-A | BLENDING A DIENE BASED ELASTOMER, A REINFROCEMENT FILLER COMPRISED OF PRECIPITATED SILICA AND CARBON BLACK, A PREFORMED COMPOSITE OF MICROCRYSTALLINE WAX, SILICA COUPLING AGENT, ANTIDEGRADANT, VULCANIZATION PROMOTER AND CARBON BLACK | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-04-25 | — | — | US | claimed |
| EP-0764688-B1 | High performance blend for tire treads | GOODYEAR TIRE & RUBBER (US) | 2000-02-23 | — | — | EP | claimed |
| EP-0941872-A2 | Rubber composition reinforced with silica and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-09-15 | — | — | EP | claimed |
| EP-0764688-A1 | High performance blend for tire treads | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | claimed |
| US-5534592-A | POLYBUTADIENE RUBBER BLEND | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | DNM1 3175/4885THRB 4600/4885HTT 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.