Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780072 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1HSD17B10HPGD | |
| SCHEMBL4090243 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1HSD17B10GLA | |
| SCHEMBL7804864 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL9013304 | 0.72 | PPM1B (0.39) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL2873702 | 0.71 | PPM1B (0.38) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL9013023 | 0.70 | PPM1B (0.42) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL13002242 | 0.69 | PPM1B (0.52) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| Ethane SCHEMBL23063636 | 0.68 | PPM1B (0.41) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL9013063 | 0.66 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 | |
| SCHEMBL13002241 | 0.66 | PPM1B (0.41) | ALDH1A1KMT2AMEN1PPM1BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090288855-A1 | POSITIVE-TYPE RADIATION-SENSITIVE RESIN COMPOSITION FOR PRODUCING A METAL-PLATING FORMED MATERIAL, TRANSCRIPTION FILM AND PRODUCTION METHOD OF A METAL-PLATING FORMED MATERIAL | JSR CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20070031758-A1 | Positive-type radiation-sensitive resin composition for producing a metal-plating formed material, transcription film and production method of a metal-plating formed material | JSR CORPORATION (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20040138242-A1 | Dihydropyrimidines and uses thereof | MERCK AND CO., INC. | 2004-07-15 | — | — | US | disclosed |
| US-20040053158-A1 | Onium salts and the use therof as latent acids | CIBA SPECIALTY CHEMICALS CORP. | 2004-03-18 | — | — | US | disclosed |
| US-6512020-B1 | Photosensitive acid-donors in chemically amplified resist formulations. activated by irradiation with actinic electromagnetic radiation and electron beams. | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138242-A1 | Dihydropyrimidines and uses thereof | QDPR, DPYD, ADRA1D | ALDH1A1 73/4885KMT2A 2204/4885MEN1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.