Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27494194 | 0.94 | — | — | |
| SCHEMBL1242049 | 0.92 | — | — | |
| SCHEMBL4469170 | 0.88 | KDM4E (0.34) | PDCD1CD274KDM4E | |
| SCHEMBL6380921 | 0.86 | PTPN1 (0.32) | KDM4E | |
| SCHEMBL4463931 | 0.85 | PTAFR (0.33) | — | |
| SCHEMBL4457465 | 0.84 | CDC25B (0.35) | PDCD1CD274 | |
| SCHEMBL4465018 | 0.84 | GSTP1 (0.36) | TRPA1KDM4E | |
| SCHEMBL5721854 | 0.83 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL27757699 | 0.83 | CDC25A (0.34) | PDCD1CD274 | |
| SCHEMBL4478710 | 0.81 | PPARG (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569651-B2 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2009-08-04 | — | — | US | disclosed |
| US-7342078-B2 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-03-11 | — | — | US | disclosed |
| US-20060020096-A1 | Transition metal compound, ligand system, catalyst system and its use for the polymerization and copolymerization of olefins | SCHOTTEK JORG | 2006-01-26 | — | — | US | disclosed |
| CN-1191285-C | Ethylene/alpha-olefin/unconjugated polyene copolymer rubber, rubber composition for sealing, molded rubber for sealing, and process for producing the molded rubber | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | BASELL POLYPROPYLEN GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| EP-1294733-A1 | BRIDGED BIS(INDENYL)METALLOCENE COMPOUNDS | ExxonMobil Chemical Patents Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002002575-A1 | METALLOCENES WITH A BRIDGED 4-PHENYL-INDENYL-LIGAND FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2002-01-10 | — | — | WO | disclosed |
| CN-1310730-A | Ethylene-alpha-olefin-nonconjugated polyene copolymer rubber, rubber composition for sealing, molded rubber article for sealing, and process for producing molded article | MITSUI CHEMICALS INC (JP) | 2001-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149199-A1 | Transition metal compound, ligand system, catalyst system and the use of the latter for polymerisation and copolymerisation of olefins | PORCN, PGR, PPOX | PDCD1 178/4885CD274 49/4885TSHR 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.