Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457060 | 0.85 | HDAC6 (0.47) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL3042449 | 0.79 | LMNA (0.43) | KDM4EHSD17B10DPP4DPP8GAA | |
| SCHEMBL4457005 | 0.76 | POLB (0.48) | POLBALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL4453442 | 0.75 | SMN1; SMN2 (0.62) | POLBTDP1ALDH1A1HPGDMAPT | |
| SCHEMBL309078 | 0.74 | DPP4 (0.41) | POLBTDP1KDM4EDPP4DPP8 | |
| SCHEMBL4458421 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ETP53GAAMAPT | |
| SCHEMBL4453299 | 0.72 | DPP4 (0.45) | TDP1ALDH1A1KDM4ETP53DPP4 | |
| SCHEMBL3042416 | 0.71 | DPP4 (0.41) | TDP1DPP4DPP8LMNAADORA2B | |
| SCHEMBL14291769 | 0.71 | DPP4 (0.49) | TDP1ALDH1A1KDM4EHSD17B10DPP4 | |
| SCHEMBL4462916 | 0.71 | RXFP1 (0.47) | POLBKDM4EGAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626964-B1 | NEW BENZIMIDAZOLE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-01-21 | — | — | EP | claimed |