Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457674 | 0.81 | MMP1 (0.52) | MMP1MMP3MMP2FCER2LMNA | |
| SCHEMBL3477645 | 0.78 | CTSS (0.58) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL6807421 | 0.74 | NPC1 (0.62) | MMP1MMP3FCER2CTSLPTPN1 | |
| SCHEMBL6807425 | 0.74 | NPC1 (0.62) | MMP1MMP3FCER2CTSLPTPN1 | |
| SCHEMBL6808320 | 0.74 | PPARG (0.57) | MMP1MMP3FCER2CTSL | |
| SCHEMBL6808317 | 0.74 | PPARG (0.57) | MMP1MMP3FCER2CTSL | |
| SCHEMBL6828028 | 0.74 | MEN1 (0.70) | MMP1MMP3FCER2LMNAMMP9 | |
| SCHEMBL6828040 | 0.74 | MEN1 (0.70) | MMP1MMP3FCER2LMNAMMP9 | |
| SCHEMBL6801630 | 0.73 | CTSL (0.66) | CTSL | |
| SCHEMBL6801635 | 0.73 | CTSL (0.66) | CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507568-B2 | Three dimensional coordinates of HPTPbeta | THE PROCTOR & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20040077065-A1 | Three dimensional coordinates of HPTPbeta | THE PROCTER & GAMBLE COMPANY | 2004-04-22 | — | — | US | disclosed |