SCHEMBL4458244

SCHEMBL4458244

CCc1ccc(C(=O)C2(O)CCCCC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
RAB9A P51151 5/20 0.48
PLK1 P53350 1/20 0.44
CHRM2 P08172 1/20 0.43
CYP2D6 P10635 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
CHRM3 P20309 1/20 0.43
DRD3 P35462 1/20 0.43
OPRD1 P41143 1/20 0.43
KCNH2 Q12809 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
HRH3 Q9Y5N1 1/20 0.43
CTSK P43235 1/20 0.40
NPC1 O15118 4/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28675638 0.87 PLK1 (0.47) ALDH1A1RAB9APLK1OPRD1NPC1
SCHEMBL28496268 0.83 MAPT (0.44) ALDH1A1RAB9ACYP2D6NPC1KMT2A
SCHEMBL27482835 0.82 THRA (0.56) ALDH1A1KMT2AMEN1
SCHEMBL3973355 0.81 CYP4A11 (0.41) HRH3TDP1SMN1; SMN2TSHRHTT
SCHEMBL256587 0.80 ALDH1A1 (0.45) ALDH1A1RAB9ANPC1KMT2ATDP1
SCHEMBL28505006 0.80 RAB9A (0.41) ALDH1A1RAB9ANPC1KMT2ATDP1
SCHEMBL11988840 0.80 ALDH1A1 (0.42) ALDH1A1RAB9APLK1NPC1KMT2A
SCHEMBL6696391 0.80 SRD5A2 (0.39) ALDH1A1RAB9ANPC1SMN1; SMN2TSHR
SCHEMBL10943813 0.80 CES2 (0.39)
SCHEMBL10050636 0.78 HRH3 (0.39) RAB9AHRH3NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369406-B Photocatalytic synthesis method and application of 1-hydroxycyclohexyl phenyl ketone compound 甘肃金盾化工有限责任公司 2021-12-14 CN disclosed
EP-1760102-B1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO LTD (JP) 2013-04-24 EP disclosed
EP-2065444-A1 PHOTOPOLYMERIZABLE COMPOSITION THREE BOND CO., LTD. (JP) 2009-06-03 EP disclosed
EP-1760102-A1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO., LTD. (JP) 2007-03-07 EP disclosed