Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911927 | 0.76 | TAAR1 (0.41) | CA7CA14 | |
| SCHEMBL2652155 | 0.73 | FOLH1 (0.50) | CA4CA6CA7CA14MAPT | |
| SCHEMBL15372424 | 0.72 | TRPA1 (0.34) | — | |
| SCHEMBL777976 | 0.72 | TAAR1 (0.42) | — | |
| SCHEMBL177737 | 0.71 | CA4 (0.45) | LIPGENPP2CA4CA6CA5A | |
| SCHEMBL30958878 | 0.71 | IDO1 (0.46) | CA4CA7CA14MAPT | |
| SCHEMBL12663117 | 0.71 | LIPE (0.30) | LIPE | |
| SCHEMBL2650422 | 0.70 | ALDH1A1 (0.53) | CA5AMAPT | |
| SCHEMBL257991 | 0.68 | CA4 (0.45) | LIPGENPP2CA4CA6CA5A | |
| SCHEMBL779948 | 0.68 | CALM1 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2073816-A2 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008063300-A2 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |