SCHEMBL4459726

SCHEMBL4459726

CC(c1ccccc1)C(OP(OC(c1ccccc1)(c1ccccc1)C(C)c1ccccc1)OC(c1ccccc1)(c1ccccc1)C(C)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
TAAR1 Q96RJ0 3/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33
RIPK1 Q13546 1/20 0.33
CYP2D6 P10635 2/20 0.32
CYP1A2 P05177 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
LMNA P02545 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
KIF11 P52732 2/20 0.32
CACNA1F O60840 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459729 0.85 ALDH1A1 (0.35) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL9494139 0.81 CYP2D6 (0.39) MAPK1TAAR1ALDH1A1ALOX15RIPK1
SCHEMBL703112 0.80 MAPK1 (0.35) MAPK1TAAR1ALDH1A1ALOX15RIPK1
SCHEMBL5147516 0.78 TAAR1 (0.36) MAPK1TAAR1ALDH1A1ALOX15RIPK1
SCHEMBL4452175 0.78 LMNA (0.37) TAAR1RIPK1CYP1A2LMNAKCNN4
SCHEMBL5147521 0.76 CYP1A2 (0.37) MAPK1ALDH1A1ALOX15CYP2D6CYP1A2
SCHEMBL6741619 0.73 TAAR1 (0.41) MAPK1TAAR1ALDH1A1RIPK1CYP2D6
SCHEMBL28972220 0.73 SRC (0.40)
SCHEMBL4451203 0.71 MAPK1 (0.39) MAPK1TAAR1ALDH1A1ALOX15RIPK1
SCHEMBL3482030 0.71 KEAP1 (0.37) MAPK1ALDH1A1LMNAKDM4EKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612148-B2 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2009-11-03 US disclosed
US-20080146733-A1 Hydrogenation catalyst composition and method for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2008-06-19 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed