Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460006 | 1.00 | KIF11 (0.44) | KIF11SIRT2DNMT1KDM4E | |
| SCHEMBL4456589 | 0.82 | MEN1 (0.43) | KIF11KDM4E | |
| SCHEMBL4456592 | 0.82 | MEN1 (0.43) | KIF11KDM4E | |
| SCHEMBL2816101 | 0.79 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL27558321 | 0.79 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL2816104 | 0.79 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL4451777 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL4457435 | 0.75 | CSNK1D (0.46) | — | |
| SCHEMBL4457438 | 0.75 | CSNK1D (0.46) | — | |
| SCHEMBL4458423 | 0.75 | ELOVL1 (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151744-A1 | S-NITROSOMERCAPTO COMPOUNDS AND RELATED DERIVATIVES | GALLEON PHARMACEUTICALS, INC. (US) | 2009-12-17 | — | — | WO | disclosed |