Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065982 | 0.85 | ADORA2A (0.48) | ENPP1ENPP3 | |
| SCHEMBL502621 | 0.75 | ENPP1 (0.52) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL1035726 | 0.74 | ENPP1 (0.51) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL8509835 | 0.73 | ENPP1 (0.50) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL28078340 | 0.68 | POLG (0.36) | ENPP1P2RY2P2RY1P2RY11 | |
| SCHEMBL21065572 | 0.68 | LMNA (0.47) | ENPP1 | |
| SCHEMBL31314844 | 0.67 | ENPP1 (0.72) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL27721221 | 0.66 | FGFR1 (0.47) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL5089696 | 0.66 | ENPP1 (0.46) | ENPP1ENPP3P2RX1P2RX3P2RX2 | |
| SCHEMBL283730 | 0.64 | FGFR1 (0.51) | ENPP1ENPP3P2RY2P2RY1P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354524-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120065387-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | disclosed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7592446-B2 | Useful in structural determinations, particularly by X-ray crystallographic techniques; useful as food supplements | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-09-22 | — | — | US | disclosed |
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-03-20 | — | — | US | disclosed |
| WO-2002077002-A2 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055016-A1 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | SELENOI, NT5C3B, RNGTT | ENPP1 51/4885ENPP3 57/4885ENTPD1 245/4885 |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | ENPP1 49/4885ENPP3 46/4885ENTPD1 252/4885 |
| US-20120065387-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | ENPP1 49/4885ENPP3 46/4885ENTPD1 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.