SCHEMBL4460087

SCHEMBL4460087

CC1(C)CC2(CC(C)(C)c3cc(OCCC4CCCCC4)c(O)cc32)c2cc(O)c(OCCC3CCCCC3)cc21

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.39
IDO1 P14902 3/20 0.38
EHMT2 Q96KQ7 1/20 0.38
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
HPGD P15428 8/20 0.36
OPRM1 P35372 1/20 0.36
PPARG P37231 1/20 0.35
SCN9A Q15858 1/20 0.35
C5AR1 P21730 1/20 0.35
MCHR1 Q99705 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4461712 0.87 CGAS (0.39) HPGD
SCHEMBL4459045 0.81 OPRM1 (0.33) OPRM1
SCHEMBL4464095 0.79 RXRA (0.33) OPRM1
SCHEMBL4455722 0.79 OPRM1 (0.42) OPRM1
SCHEMBL4469326 0.78 RXRA (0.38) OPRM1PPARG
SCHEMBL4474777 0.78 APP (0.36) OPRM1PPARG
SCHEMBL4462303 0.78 DAO (0.40) OPRM1
SCHEMBL4459032 0.78 KMT2A (0.32) PTGES
SCHEMBL4460159 0.77 RXRA (0.38) OPRM1PPARG
SCHEMBL8019962 0.77 HNF4A (0.41) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed