Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839968 | 0.89 | CYP2D6 (0.49) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL24274700 | 0.84 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL21579184 | 0.84 | CYP2D6 (0.47) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL20362787 | 0.83 | CYP2D6 (0.74) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL17013838 | 0.83 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2C19CYP2C9HSD17B10 | |
| SCHEMBL21143034 | 0.82 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL17013844 | 0.82 | ALDH1A1 (0.47) | CYP2D6CYP1A2CYP2C19CYP2C9KMT2A | |
| SCHEMBL13990680 | 0.80 | CYP2D6 (0.41) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL976289 | 0.78 | ALDH1A1 (0.39) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A | |
| SCHEMBL20312980 | 0.78 | CYP1A2 (0.36) | CYP2D6CYP1A2CYP2C19CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635595-B2 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R | 2009-12-22 | — | — | US | disclosed |
| US-7635595-B2 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R | 2009-12-22 | — | — | US | disclosed |
| US-20080299666-A1 | Novel Peptide-Based Borono-Lectin (PBL) Sensors | UNIVERSITY OF SOUTH CAROLINA (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080299666-A1 | Novel Peptide-Based Borono-Lectin (PBL) Sensors | UNIVERSITY OF SOUTH CAROLINA (US) | 2008-12-04 | — | — | US | disclosed |
| US-20050158245-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2005-07-21 | — | — | US | disclosed |
| US-6804544-B2 | GLUCOSE MEASUREMENT | MINIMED, INC. | 2004-10-12 | — | — | US | disclosed |
| EP-0862648-B1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MEDTRONIC MINIMED INC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-6750311-B1 | CONCENTRATION OF BLOOD GLUCOSE; BORONATE COMPLEX WITH A FLUORESCENT DYE; POLYURETHANE OR POLYUREA BIOCOMPATABLE MATRIX BY REACTION OF A DIISOCYANATE WITH A POLYMERIC DIOL OR POLYMERIC DIAMINE | MINIMED INC. | 2004-06-15 | — | — | US | disclosed |
| US-20040087842-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2004-05-06 | — | — | US | disclosed |
| US-20020018843-A1 | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. | 2002-02-14 | — | — | US | disclosed |
| US-6319540-B1 | IMMOBILIZING BORONIC ACID MOIETY IN SOLID SUPPORT BY ATTACHING TO A POLYMER MATRIX | MINIMED INC. | 2001-11-20 | — | — | US | disclosed |
| US-6011984-A | Detection of biological molecules using chemical amplification and optical sensors | MINIMED INC. (US) | 2000-01-04 | — | — | US | disclosed |
| US-6002954-A | IMPLANTABLE AMPLIFICATION SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998022820-A9 | DETECTION OF BIOLOGICAL MOLECULES USING BORONATE-BASED CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | — | 1998-09-11 | — | — | WO | disclosed |
| EP-0862648-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | Minimed Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1998022820-A1 | DETECTION OF BIOLOGICAL MOLECULES USING BORONATE-BASED CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | LAWRENCE LIVERMORE NATIONAL LABORATORY (US) | 1998-05-28 | — | — | WO | disclosed |
| WO-1997019188-A1 | DETECTION OF BIOLOGICAL MOLECULES USING CHEMICAL AMPLIFICATION AND OPTICAL SENSORS | MINIMED, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158245-A1 | Fluorescent probes for saccharrides | H1-3, H1-0, H1-2 | CYP2D6 2616/4885CYP1A2 4384/4885CYP2C19 4664/4885 |
| US-20080299666-A1 | Novel Peptide-Based Borono-Lectin (PBL) Sensors | LGALS3BP, LGALS1, BCAP31 | CYP2D6 4655/4885CYP1A2 4844/4885CYP2C19 4751/4885 |
| US-20040087842-A1 | Fluorescent probes for saccharrides | ST6GAL1, SLC5A1, CA6 | CYP2D6 1936/4885CYP1A2 4250/4885CYP2C19 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.