Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24274700 | 0.94 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL21143034 | 0.92 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL21579184 | 0.91 | CYP2D6 (0.47) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL13990680 | 0.90 | CYP2D6 (0.41) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL4460221 | 0.89 | CYP2D6 (0.50) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL13600367 | 0.85 | CYP1A2 (0.37) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL15031011 | 0.84 | CYP1A2 (0.36) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL20312980 | 0.84 | CYP1A2 (0.36) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL976289 | 0.84 | ALDH1A1 (0.39) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL20362787 | 0.83 | CYP2D6 (0.74) | CYP2D6CYP1A2CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025694-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-01-26 | — | — | US | disclosed |
| US-11369295-B2 | Silicone hydrogel based fluorescent assay and contact lens | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-06-28 | — | — | US | disclosed |
| US-11034952-B2 | Aptamer methods and compositions | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-06-15 | — | — | US | disclosed |
| WO-2020240258-A1 | COMPACT DEVICE FOR NON-INVASIVE MEASUREMENT OF MARKERS IN PHYSIOLOGICAL FLUIDS | TOMASOV VIKTOR (EE) | 2020-12-03 | — | — | WO | disclosed |
| US-20200229740-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-07-23 | — | — | US | disclosed |
| US-20190185845-A1 | APTAMER METHODS AND COMPOSITIONS | NATIONAL SCIENCE FOUNDATION | 2019-06-20 | — | — | US | disclosed |
| US-20160076021-A1 | APTAMER METHODS AND COMPOSITIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-03-17 | — | — | US | disclosed |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| EP-1671118-B1 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIV MARYLAND (US) | 2011-11-02 | — | — | EP | disclosed |
| US-7524985-B2 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | TERUMO KABUSHIKI KAISHA (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20080319288-A1 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | TERUMO KABUSHIKI KAISHA (JP) | 2008-12-25 | — | — | US | disclosed |
| US-7388110-B2 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | TERUMO KABUSHIKI KAISHA (JP) | 2008-06-17 | — | — | US | disclosed |
| US-20080096281-A1 | Cyanide Sensing Compounds and Uses Thereof | GEDDES, CHRIS, DR. | 2008-04-24 | — | — | US | disclosed |
| US-20080021236-A1 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | TERUMO KABUSHIKI KAISHA (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1671118-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | University of Maryland Biotechnology Institute (US) | 2006-06-21 | — | — | EP | disclosed |
| US-20050158245-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2005-07-21 | — | — | US | disclosed |
| WO-2005029033-A2 | CYANIDE SENSING COMPOUNDS AND USES THEREOF | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2005-03-31 | — | — | WO | disclosed |
| US-20040087842-A1 | Fluorescent probes for saccharrides | LAKOWICZ JOSEPH R (US) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050158245-A1 | Fluorescent probes for saccharrides | H1-3, H1-0, H1-2 | CYP2D6 2616/4885CYP1A2 4384/4885CYP2C19 4664/4885 |
| US-20230025694-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | CD44, CRYAA, IGFBP1 | CYP2D6 4081/4885CYP1A2 4634/4885CYP2C19 3942/4885 |
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | CYP2D6 721/4885CYP1A2 1046/4885CYP2C19 1347/4885 |
| US-20040087842-A1 | Fluorescent probes for saccharrides | ST6GAL1, SLC5A1, CA6 | CYP2D6 1936/4885CYP1A2 4250/4885CYP2C19 4725/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | CYP2D6 721/4885CYP1A2 1046/4885CYP2C19 1347/4885 |
| US-11369295-B2 | Silicone hydrogel based fluorescent assay and contact lens | CD44, CRYAA, IGFBP1 | CYP2D6 4081/4885CYP1A2 4634/4885CYP2C19 3942/4885 |
| US-20080319288-A1 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | ACMSD, QPCT, B3GNT2 | CYP2D6 466/4885CYP1A2 1737/4885CYP2C19 653/4885 |
| US-20200229740-A1 | Silicone Hydrogel Based Fluorescent Assay and Contact Lens | CD44, CRYAA, IGFBP1 | CYP2D6 4081/4885CYP1A2 4634/4885CYP2C19 3942/4885 |
| US-20080021236-A1 | Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor | ACMSD, QPCT, B3GNT2 | CYP2D6 476/4885CYP1A2 1882/4885CYP2C19 663/4885 |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | GCKR, SYMPK, SUCNR1 | CYP2D6 721/4885CYP1A2 1046/4885CYP2C19 1347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.