SCHEMBL976289

SCHEMBL976289

CN(Cc1ccccc1B(O)O)Cc1c2ccccc2c(CN(C)Cc2ccccc2B(O)O)c2cc(C(=O)O)ccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
PPARG P37231 1/20 0.39
KDM4E B2RXH2 4/20 0.37
ACE2 Q9BYF1 3/20 0.37
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 2/20 0.36
MEN1 O00255 1/20 0.36
TNNI3 P19429 1/20 0.36
TNNT2 P45379 1/20 0.36
TNNC1 P63316 1/20 0.36
KMT2A Q03164 1/20 0.36
CSNK2A1 P68400 1/20 0.36
GRIN2D O15399 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2C Q14957 1/20 0.35
ACHE P22303 2/20 0.34
BCHE P06276 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16075822 0.89 ACHE (0.37) ALDH1A1HPGDPPARGMEN1KMT2A
SCHEMBL975690 0.87 KIF11 (0.41) ALDH1A1KDM4EMEN1KMT2AACHE
SCHEMBL1839968 0.84 CYP2D6 (0.49) ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19
SCHEMBL976748 0.84 KDM4E (0.39) ALDH1A1HPGDPPARGKDM4EACE2
SCHEMBL20312980 0.81 CYP1A2 (0.36) ALDH1A1HPGDKDM4ECYP1A2CYP2D6
SCHEMBL24274700 0.79 CYP2D6 (0.44) ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19
SCHEMBL14016096 0.78 HPGD (0.45) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL4460221 0.78 CYP2D6 (0.50) KDM4ECYP1A2CYP2D6CYP2C19MEN1
SCHEMBL21143034 0.78 CYP2D6 (0.42) ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19
SCHEMBL21579184 0.76 CYP2D6 (0.47) ALDH1A1KDM4ECYP1A2CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7873398-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2011-01-18 US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
US-7450980-B2 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2008-11-11 US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 EP disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 EP disclosed
US-20050221277-A1 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2005-10-06 US disclosed
EP-1582144-A1 Intracorporeal substance measuring assembly TERUMO KABUSHIKI KAISHA (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 167/4885HPGD 442/4885PPARG 4529/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 273/4885HPGD 632/4885PPARG 4502/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 273/4885HPGD 632/4885PPARG 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.