SCHEMBL446031

SCHEMBL446031

CC(C)(C)CC(C)(C)c1ccc(C(=O)OC(=O)c2ccc(C(C)(C)CC(C)(C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.55
CYP3A4 P08684 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MDH1 P40925 13/20 0.45
MDH2 P40926 13/20 0.45
HIF1A Q16665 3/20 0.41
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27932707 0.87 SHBG (0.53) SHBGCYP3A4SMN1; SMN2MDH1MDH2
SCHEMBL448363 0.83 NPC1 (0.48) CYP3A4SMN1; SMN2MAPT
SCHEMBL448814 0.81 SHBG (0.59) SHBGCYP3A4SMN1; SMN2
SCHEMBL8769748 0.79 SHBG (0.57) SHBGCYP3A4SMN1; SMN2MDH1MDH2
SCHEMBL446399 0.78 HDAC1 (0.57) HIF1AMAPT
SCHEMBL448364 0.77 NPC1 (0.54) SMN1; SMN2HIF1AMAPT
SCHEMBL10529183 0.77 MAPT (0.69) SHBGCYP3A4SMN1; SMN2MDH1MDH2
SCHEMBL20878570 0.76 SHBG (0.53) SHBGCYP3A4SMN1; SMN2
SCHEMBL5687900 0.76 TNF (0.56) HIF1AMAPT
SCHEMBL446032 0.76 CNR2 (0.48) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290868-B2 Biodegradable nonwoven fabric and fiber product using the same JNC CORPORATION (JP) 2016-03-22 US disclosed
EP-2422005-B1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORP (JP) 2013-12-04 EP disclosed
US-20120064789-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC CORPORATION (JP) 2012-03-15 US disclosed
EP-2422005-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME JNC Corporation (JP) 2012-02-29 EP disclosed
WO-2010122806-A1 BIODEGRADABLE NONWOVEN FABRIC AND FIBER PRODUCT USING THE SAME CHISSO CORPORATION (JP) 2010-10-28 WO disclosed