Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MDH1 | P40925 | 11/20 | 0.40 |
| ▸ | MDH2 | P40926 | 11/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615735 | 0.82 | NPC1 (0.45) | SMN1; SMN2POLBALDH1A1HDAC1MEN1 | |
| SCHEMBL448814 | 0.82 | SHBG (0.59) | SHBGCYP3A4SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL446031 | 0.79 | SHBG (0.55) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL27932707 | 0.78 | SHBG (0.53) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL20878570 | 0.78 | SHBG (0.53) | SHBGCYP3A4SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL38841 | 0.77 | HDAC1 (0.59) | SMN1; SMN2POLBHIF1AALDH1A1HDAC1 | |
| SCHEMBL7718602 | 0.77 | ESR1 (0.48) | CYP3A4SMN1; SMN2POLBHIF1AALDH1A1 | |
| SCHEMBL9457427 | 0.77 | CYP3A4 (0.54) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL27704404 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2POLBHIF1AALDH1A1HDAC1 | |
| SCHEMBL1021439 | 0.75 | LMNA (0.42) | SMN1; SMN2POLBALDH1A1HDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659738-B1 | N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers | EASTMAN KODAK CO (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5616797-A | USED IN ELECTROPHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0659738-A1 | N-(Carbonyl, carbonimidoyl, carbonothioyl) sulfonamide charge control agents and toners and developers | EASTMAN KODAK COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| US-5405727-A | Electrophotography | EASTMAN KODAK COMPANY (US) | 1995-04-11 | — | — | US | disclosed |