SCHEMBL446165

SCHEMBL446165

[N-]=[N+]=NOC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 2/20 0.73
▸ P2RY1 P47900 4/20 0.68
▸ ADORA1 P30542 4/20 0.68
▸ P2RY2 P41231 3/20 0.68
▸ SMN1; SMN2 Q16637 3/20 0.68
▸ SRC P12931 2/20 0.68
▸ TRPM2 O94759 2/20 0.68
▸ TAS1R3 Q7RTX0 2/20 0.68
▸ TAS1R1 Q7RTX1 2/20 0.68
▸ DNPH1 O43598 1/20 0.68
▸ PRKAB2 O43741 1/20 0.68
▸ LDHA P00338 1/20 0.68
▸ ADRB2 P07550 1/20 0.68
▸ FBP1 P09467 1/20 0.68
▸ PRKAG1 P54619 1/20 0.68
▸ PRKAA2 P54646 1/20 0.68
▸ PDE4D Q08499 1/20 0.68
▸ KCNH2 Q12809 1/20 0.68
▸ PRKAA1 Q13131 1/20 0.68
▸ PDE3A Q14432 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18486637 0.88 ADORA1 (0.67) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL18486728 0.85 RNASEL (0.65) P2RY1ADORA1P2RY2SMN1; SMN2SRC
SCHEMBL16682237 0.84 AHCY (1.00) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL26807050 0.84 AHCY (1.00) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL15371600 0.84 AHCY (1.00) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL3522303 0.84 RNASEL (0.67) P2RY1ADORA1P2RY2SMN1; SMN2SRC
SCHEMBL10997946 0.84 ADORA1 (0.76) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL12963362 0.84 ADORA1 (0.76) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL7803298 0.84 ADORA1 (0.76) AHCYP2RY1ADORA1P2RY2SMN1; SMN2
SCHEMBL2040670 0.84 ADORA1 (0.76) AHCYP2RY1ADORA1P2RY2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060246438-A1 Methods for the chemical and physical modification of nanotubes, methods for linking the nanotubes, methods for the directed positioning of nanotubes, and uses thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2006-11-02 — — US claimed
EP-1549662-A1 METHODS FOR THE CHEMICAL AND PHYSICAL MODIFICATION OF NANOTUBES, METHODS FOR LINKING THE NANOTUBES, METHODS FOR THE DIRECTED POSITIONING OF NANOTUBES, AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-07-06 — — EP claimed
EP-1017725-A4 METHOD OF AFFINITY CROSS-LINKING BIOLOGICALLY ACTIVE, IMMUNOGENIC PEPTIDES TO ANTIBODIES INNEXUS BIOTECHNOLOGY INTERNAT (CA) 2004-06-30 — — EP claimed
WO-2004020450-A1 METHODS FOR THE CHEMICAL AND PHYSICAL MODIFICATION OF NANOTUBES, METHODS FOR LINKING THE NANOTUBES, METHODS FOR THE DIRECTED POSITIONING OF NANOTUBES, AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-03-11 — — WO claimed
EP-1017725-A1 METHOD OF AFFINITY CROSS-LINKING BIOLOGICALLY ACTIVE, IMMUNOGENIC PEPTIDES TO ANTIBODIES Immpheron Incorporated (US) 2000-07-12 — — EP claimed
WO-1999014244-A1 METHOD OF AFFINITY CROSS-LINKING BIOLOGICALLY ACTIVE, IMMUNOGENIC PEPTIDES TO ANTIBODIES KOHLER HEINZ (US) 1999-03-25 — — WO claimed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 — — EP disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 — — US disclosed
EP-4658664-A1 CAP ANALOGS WITH 5'-TERMINAL ACYCLIC GUANOSINE DERIVATIVE CureVac SE (DE) 2025-12-10 — — EP disclosed
EP-4045498-B1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS UNIV CALIFORNIA (US) 2025-12-03 — — EP disclosed
EP-4466074-A1 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF The Broad Institute Inc. (US) 2024-11-27 — — EP disclosed
WO-2024160895-A1 CAP ANALOGS WITH 5'-TERMINAL ACYCLIC GUANOSINE DERIVATIVE CureVac SE (DE) 2024-08-08 — — WO disclosed
WO-2023007019-A9 CAP ANALOGS HAVING AN ACYCLIC LINKER TO THE GUANINE DERIVATIVE NUCLEOBASE CureVac SE (DE) 2024-02-29 — — WO disclosed
WO-1996013522-A9 COMPLEMENTARILY BONDED TWO- AND THREE-DIMENSIONAL SUPRAMOLECULAR STRUCTURES — 1996-09-12 — — WO disclosed
WO-1996013522-A1 COMPLEMENTARILY BONDED TWO- AND THREE-DIMENSIONAL SUPRAMOLECULAR STRUCTURES BURSTEIN LABORATORIES, INC. (US) 1996-05-09 — — WO disclosed
EP-0165313-B1 NUCLEIC ACID HYBRIDIZATION ASSAY HRI RESEARCH, INC. (US) 1989-11-15 — — EP disclosed
US-4599303-A PSORALEN DERIVATIVES HRI ASSOCIATES, INC. (US) 1986-07-08 — — US disclosed
EP-0165313-A4 NUCLEIC ACID HYBRIDIZATION ASSAY. HRI RES INC (US) 1986-05-16 — — EP disclosed
EP-0165313-A1 NUCLEIC ACID HYBRIDIZATION ASSAY. HYDROCARBON RESEARCH INC (US) 1985-12-27 — — EP disclosed
WO-1985002628-A1 NUCLEIC ACID HYBRIDIZATION ASSAY HRI RESEARCH, INC. (US) 1985-06-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 AHCY 917/4885P2RY1 4435/4885ADORA1 2227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback