Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 8/20 | 0.41 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172322 | 0.98 | MMP2 (0.41) | MMP2MMP13CHEK2MAP2K4MAPK1 | |
| SCHEMBL29751019 | 0.86 | CHEK2 (0.48) | CHEK2PKN1PKN2CHEK1 | |
| SCHEMBL446292 | 0.86 | CHEK2 (0.48) | CHEK2PKN1PKN2CHEK1 | |
| SCHEMBL119640 | 0.84 | TDP1 (0.44) | KMT2AMEN1TSHRHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL6052079 | 0.82 | TDP1 (0.43) | KMT2AMEN1HSD17B10CD40CD40LG | |
| SCHEMBL8424370 | 0.82 | TDP1 (0.43) | KMT2AMEN1HSD17B10CD40CD40LG | |
| Water SCHEMBL30938808 | 0.82 | TDP1 (0.43) | KMT2AMEN1HSD17B10CD40CD40LG | |
| SCHEMBL3726621 | 0.82 | SLC2A1 (0.41) | HTR1AHTR1DHTR1BCD40CD40LG | |
| SCHEMBL6216873 | 0.82 | F2 (0.46) | — | |
| SCHEMBL7325912 | 0.82 | CD40 (0.38) | TSHRCD40CD40LG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472149-B1 | HETEROCYCLIC PROLINAMIDE DERIVATIVES | Orion Ophthalmology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| EP-3275440-B1 | NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2022-05-04 | — | — | EP | claimed |
| EP-3849552-A1 | COMPOSITIONS COMPRISING A CRAC INHIBITOR AND A CORTICOSTEROID AND METHODS OF USE THEREOF | Rhizen Pharmaceuticals AG (CH) | 2021-07-21 | — | — | EP | claimed |
| WO-2020053834-A1 | COMPOSITIONS COMPRISING A CRAC INHIBITOR AND A CORTICOSTEROID AND METHODS OF USE THEREOF | RHIZEN PHARMACEUTICALS SA (CH) | 2020-03-19 | — | — | WO | claimed |
| WO-2015187827-A1 | NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2015-12-10 | — | — | WO | claimed |
| CN-101686979-A | The urea modulators that the heteroaryl of fatty acid amide hydrolase replaces | JANSSEN PHARMACEUTICA NV | 2010-03-31 | — | — | CN | claimed |
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
| EP-1893599-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | AstraZeneca AB (SE) | 2008-03-05 | — | — | EP | claimed |
| WO-2007092403-A1 | N-PHENYLBENZOTRIAZOLYL C-KIT INHIBITORS | OSI PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | claimed |
| WO-2006134378-A1 | COMPOUNDS FOR THE TREATMENT OF MULTI-DRUG RESISTANT BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | WO | claimed |
| JP-10077412-A | — | — | None | — | — | JP | disclosed |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES | 2025-05-01 | — | — | US | disclosed |
| CN-111801322-B | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | 迈阿密大学 | 2024-03-15 | — | — | CN | disclosed |
| WO-2024043741-A1 | AUTOTAXIN INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 | 2024-02-29 | — | — | WO | disclosed |
| US-11851428-B2 | Activator of TREK (TWIK RElated K+channels) channels | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-12-26 | — | — | US | disclosed |
| EP-0822234-A1 | Addition-curable silicone elastomers having a reduced compression set | Wacker-Chemie GmbH (DE) | 1998-02-04 | — | — | EP | disclosed |
| EP-0131161-B1 | HEAT-DEVELOPABLE COLOR PHOTOSENSITIVE ELEMENT | KONICA CORPORATION (JP) | 1988-11-02 | — | — | EP | disclosed |
| US-4770989-A | USING A THERMAL SOLVENT AND GELATIN/POLYVINYPYRROLIDONE POLYMER MIXTURE; DIFFUSION TRANSFER QUALITY IMAGE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-09-13 | — | — | US | disclosed |
| US-4649096-A | EXPOSURE, DEVELOPMENT, ALKALI HYDROXIDE, ALKANOLAMINE, SULFITE, THIOSULFATE, P-DIHYDROXYBENZENE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| EP-0131161-A2 | Heat-developable color photosensitive element | KONICA CORPORATION (JP) | 1985-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851428-B2 | Activator of TREK (TWIK RElated K+channels) channels | KCNJ11, KCNJ1, KCNJ8 | MMP2 3731/4885MMP13 4021/4885CHEK2 1202/4885 |
| US-20090163471-A1 | Tropane compounds | ADRA1B, ADRA2B, ADRB2 | MMP2 3368/4885MMP13 3082/4885CHEK2 1483/4885 |
| US-20250136592-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | MLLT3, MLLT1, YEATS2 | MMP2 3926/4885MMP13 3846/4885CHEK2 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.