SCHEMBL4463078

SCHEMBL4463078

CCCCCCCCCCCCCCCCCC(=O)Cc1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
HPGD P15428 3/20 0.54
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 1/20 0.46
FAAH O00519 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PLA2G4B P0C869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451513 1.00 L3MBTL1 (0.56) L3MBTL1TDP1HPGDKMT2AMEN1
SCHEMBL18348905 1.00 L3MBTL1 (0.56) L3MBTL1TDP1HPGDKMT2AMEN1
SCHEMBL1462314 0.93 L3MBTL1 (0.59) L3MBTL1TDP1HPGDKMT2AMEN1
SCHEMBL9362946 0.86 HSD17B3 (0.59) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL8084700 0.86 ALDH1A1 (0.66) HPGDKMT2AMEN1ALDH1A1MAPT
SCHEMBL8936320 0.86 HSD17B3 (0.59) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL9362853 0.86 HSD17B3 (0.59) KMT2AMEN1ALDH1A1CYP1A2CYP3A4
SCHEMBL1411319 0.85 L3MBTL1 (0.62) L3MBTL1TDP1HPGDKMT2AMEN1
SCHEMBL6206314 0.84 FAAH (0.59) KMT2AMEN1ALDH1A1MAPTFAAH
SCHEMBL9060468 0.84 KMT2A (0.66) L3MBTL1TDP1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US claimed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP claimed
US-20060025503-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers PMC CINCINNATI, INC. 2006-02-02 US claimed
EP-1621576-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-02-01 EP claimed
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP disclosed
US-20060025503-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers PMC CINCINNATI, INC. 2006-02-02 US disclosed
EP-1621576-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-02-01 EP disclosed
EP-0833861-B1 OVERBASED PVC STABILIZER CROMPTON CORP (US) 2001-05-09 EP disclosed
US-5888427-A Method for making overbased PVC stablizer WITCO CORPORATION (US) 1999-03-30 US disclosed
US-5872166-A THERMAL STABILIZERS FOR POLYVINYL CHLORIDE RESINS WITCO CORPORATION (US) 1999-02-16 US disclosed
EP-0833860-A4 METHOD FOR MAKING OVERBASED PVC STABILIZER WITCO CORP (US) 1998-10-07 EP disclosed
EP-0833861-A1 OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1998-04-08 EP disclosed
EP-0833860-A1 METHOD FOR MAKING OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1998-04-08 EP disclosed
EP-0524354-B1 Polyvinylchloride composition and stabilizers therefor WITCO CORP (US) 1997-10-01 EP disclosed
US-5656202-A Method for making overbased PVC stabilizer WITCO CORPORATION (US) 1997-08-12 US disclosed
WO-1997000907-A1 METHOD FOR MAKING OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1997-01-09 WO disclosed
WO-1997000908-A1 OVERBASED PVC STABILIZER WITCO CORPORATION (US) 1997-01-09 WO disclosed
EP-0524354-A1 Polyvinylchloride composition and stabilizers therefor WITCO CORPORATION (US) 1993-01-27 EP disclosed
US-5102933-A Heat resistance, discoloration inhibition WITCO CORPORATION (US) 1992-04-07 US disclosed