Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TST | Q16762 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362853 | 1.00 | HSD17B3 (0.59) | HSD17B3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9362946 | 1.00 | HSD17B3 (0.59) | HSD17B3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4383629 | 0.98 | HSD17B3 (0.58) | HSD17B3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL2565115 | 0.93 | HSD17B3 (0.56) | HSD17B3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL18348905 | 0.86 | L3MBTL1 (0.56) | CYP3A4ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8084700 | 0.86 | ALDH1A1 (0.66) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4463078 | 0.86 | L3MBTL1 (0.56) | CYP3A4ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4451513 | 0.86 | L3MBTL1 (0.56) | CYP3A4ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL106914 | 0.85 | CA2 (0.54) | HSD17B3ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28635322 | 0.84 | ESR1 (0.65) | HSD17B3ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512059-A | DYEING POLYUREHTANE ELASTIC FIBERS INCLUDING CHLORINE-INDUCED DEGRADATION INHIBITORS THAT DO NO ELUTE OUT | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | disclosed |
| US-5456960-A | A multicomponent yarn comprising a polyurethane elastic fiber containing one or more chlorination resistant inhibitors selected from the group consisting of oxides and hydroxides of magnesium, zinc, aluminum and hydrotalcite | TOYO BOSEKI KABUSHIHI KAISHA (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0489395-B1 | Dyed mixed knit fabric and method for its manufacture | TOYO BOSEKI (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0489395-A1 | Dyed mixed knit fabric and method for its manufacture | Toyo Boseki Kabushiki Kaisha (JP) | 1992-06-10 | — | — | EP | disclosed |