Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16267306 | 0.91 | ALDH1A1 (0.72) | ALDH1A1FAAHHSD17B10HPGDESR1 | |
| SCHEMBL9362853 | 0.86 | HSD17B3 (0.59) | ALDH1A1HSD17B10ESR1ADRA2AADORA3 | |
| SCHEMBL9362946 | 0.86 | HSD17B3 (0.59) | ALDH1A1HSD17B10ESR1ADRA2AADORA3 | |
| SCHEMBL4463078 | 0.86 | L3MBTL1 (0.56) | ALDH1A1FAAHHSD17B10HPGDCYP3A4 | |
| SCHEMBL4451513 | 0.86 | L3MBTL1 (0.56) | ALDH1A1FAAHHSD17B10HPGDCYP3A4 | |
| SCHEMBL18348905 | 0.86 | L3MBTL1 (0.56) | ALDH1A1FAAHHSD17B10HPGDCYP3A4 | |
| SCHEMBL8936320 | 0.86 | HSD17B3 (0.59) | ALDH1A1HSD17B10ESR1ADRA2AADORA3 | |
| SCHEMBL2725127 | 0.85 | ALDH1A1 (0.49) | ALDH1A1FAAHHSD17B10HPGDESR1 | |
| SCHEMBL6206314 | 0.84 | FAAH (0.59) | ALDH1A1FAAHHSD17B10ESR1ADRA2A | |
| SCHEMBL9060468 | 0.84 | KMT2A (0.66) | ALDH1A1FAAHHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165234-A | FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS | KANAKKANATT SEBASTIAN V (US) | 2000-12-26 | — | — | US | disclosed |