SCHEMBL446340

SCHEMBL446340

COc1ccccc1C(=O)OC(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.60
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
ALDH1A1 P00352 3/20 0.54
TSHR P16473 1/20 0.52
HPGD P15428 2/20 0.51
MAPT P10636 2/20 0.51
KMT2A Q03164 2/20 0.51
CTSD P07339 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
HTT P42858 1/20 0.50
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDM4E B2RXH2 1/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
XBP1 P17861 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446339 0.91 HPGD (0.59) NPC1RAB9AALDH1A1TSHRHPGD
SCHEMBL8423145 0.87 SLC6A3 (0.50) SLC6A3NPC1RAB9AALDH1A1TSHR
SCHEMBL8528111 0.87 KMT2A (0.51) SLC6A3NPC1RAB9AALDH1A1TSHR
SCHEMBL14803675 0.86 LMNA (0.61) SLC6A3NPC1RAB9AALDH1A1TSHR
SCHEMBL27660171 0.85 MAPT (0.48) SLC6A3NPC1RAB9AALDH1A1TSHR
SCHEMBL554492 0.85 HPGD (0.54) SLC6A3NPC1RAB9AALDH1A1TSHR
SCHEMBL11267813 0.85 NPC1 (0.54) SLC6A3NPC1RAB9AALDH1A1HPGD
SCHEMBL6948356 0.84 SLC6A3 (0.72) SLC6A3ALDH1A1TSHRHPGDMAPT
SCHEMBL27660170 0.83 TP53 (0.51) NPC1RAB9AALDH1A1TSHRMAPT
SCHEMBL125031 0.83 HPGD (0.56) NPC1RAB9AALDH1A1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9011734-B2 Ligand exchange thermochromic, (LETC), systems PLEOTINT, L.L.C. (US) 2015-04-21 US claimed
US-8018639-B2 Ligand exchange thermochromic, (LETC), systems PLEOTINT, L.L.C. (US) 2011-09-13 US claimed
US-20090283728-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2009-11-19 US claimed
EP-2082005-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS Pleotint, L.L.C. (US) 2009-07-29 EP claimed
US-20080100902-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, LLC (US) 2008-05-01 US claimed
WO-2008028128-A1 LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS PLEOTINT, L.L.C. (US) 2008-03-06 WO claimed
EP-0067964-B1 PROCESS FOR THE PREPARATION OF 2-ISOSORBIDE NITRATE Heinrich Mack Nachf. (DE) 1985-04-03 EP claimed
US-4417065-A ACYLATION OF ISOSORBIDE AND ESTERIFICATION WITH NITRIC ACID HEINRICH MACK NACHF. CHEM.-PHARMAZEUTISCHE FABRIK (DE) 1983-11-22 US claimed
CN-120077502-A Electrolyte, electrochemical device, secondary battery, and lithium ion secondary battery 大金工业株式会社 2025-05-30 CN disclosed
CN-222709618-U Carbohydrazide preparation facilities 山东源泰新材料有限公司 2025-04-04 CN disclosed
CN-119497914-A Negative electrode, battery, and method for coating battery material 大金工业株式会社 2025-02-21 CN disclosed
CN-119487661-A Secondary battery 大金工业株式会社 2025-02-18 CN disclosed
CN-119422259-A Surface treatment agent for electrode material, positive electrode active material, current collecting foil, negative electrode active material, conductive auxiliary agent, electrode, battery, method for producing positive electrode active material, method for producing current collecting foil, method for producing negative electrode active material, method for producing conductive auxiliary agent, and method for producing electrode 大金工业株式会社 2025-02-11 CN disclosed
CN-119340518-A Lithium secondary battery and assembly 大金工业株式会社 2025-01-21 CN disclosed
US-6005116-A HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA SANKYO COMPANY, LIMITED (JP) 1999-12-21 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed
US-5843983-A Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use SANKYO COMPANY, LIMITED (JP) 1998-12-01 US disclosed
EP-0790235-A1 Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses SANKYO COMPANY LIMITED (JP) 1997-08-20 EP disclosed
US-3970671-A XANTHENE, PRESSURE SENSITIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1976-07-20 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed