Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528108 | 0.90 | KMT2A (0.59) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL1573402 | 0.88 | LMNA (0.53) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8526794 | 0.88 | PKM (0.53) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL446340 | 0.87 | SLC6A3 (0.60) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8423145 | 0.84 | SLC6A3 (0.50) | POLBNPC1RAB9AALDH1A1SLC6A3 | |
| SCHEMBL29986971 | 0.82 | MAPT (0.57) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL322169 | 0.82 | MAPT (0.57) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| Benzoic Acid SCHEMBL28816580 | 0.81 | HTT (0.56) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL870485 | 0.81 | NPC1 (0.52) | KMT2APOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28095416 | 0.81 | MAPT (0.55) | KMT2APOLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433112-B1 | Modified gangliosides and the functional derivatives thereof | FIDIA SPA (IT) | 1998-10-28 | — | — | EP | disclosed |
| CN-1033031-C | Modified gangliosides and functional derivatives thereof | FIDIA SPA (IT) | 1996-10-16 | — | — | CN | disclosed |
| US-5424294-A | Treating central and peripheral nervous system disorders | FIDIA S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5264424-A | Modified gangliosides and the functional derivatives thereof | FIDIA S.P.A. (IT) | 1993-11-23 | — | — | US | disclosed |
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| US-4327088-A | ANTIVIRAL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-04-27 | — | — | US | disclosed |