Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446339 | 0.90 | HPGD (0.59) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL125031 | 0.86 | HPGD (0.56) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL29022476 | 0.85 | SLC6A3 (0.47) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL446340 | 0.85 | SLC6A3 (0.60) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL7172322 | 0.85 | HPGD (0.54) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL352355 | 0.84 | HTT (0.52) | HPGDALDH1A1KMT2AHTTMAPT | |
| SCHEMBL717176 | 0.83 | HPGD (0.57) | HPGDALDH1A1KMT2ACTSDHTT | |
| Methyl 2-Methoxybenzoate SCHEMBL5182927 | 0.82 | SLC6A3 (0.66) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL48968 | 0.82 | HPGD (0.59) | HPGDALDH1A1KMT2ACTSDHTT | |
| SCHEMBL383183 | 0.82 | HPGD (0.59) | HPGDALDH1A1KMT2ACTSDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427771-A1 | METHOD OF POLYCARBONATE PREPARATION BY SOLID STATE POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 2004-06-16 | — | — | EP | claimed |
| EP-1414887-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2004-05-06 | — | — | EP | claimed |
| WO-2003010218-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010219-A1 | METHOD OF POLYCARBONATE PREPARATION BY SOLID STATE POLYMERIZATION | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | claimed |
| EP-2365957-B1 | METHOD FOR MAKING CARBONATES AND ESTERS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-04-22 | — | — | EP | disclosed |
| CN-106660933-B | Method for melt polymerizing polycarbonate and polycarbonate prepared therefrom | 沙特基础工业全球技术有限公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-106459397-B | The melt reaction method of cross-linking polycarbonate | 沙特基础工业全球技术有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-106029378-B | Multilayer sheets, methods of making and using the same, and articles comprising the multilayer sheets | 沙特基础工业全球技术有限公司 | 2019-02-01 | — | — | CN | disclosed |
| CN-108699228-A | Inherently healing polycarbonates | 沙特基础工业全球技术公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-105026472-B | Polymer sheets, methods of making and using the same, and articles comprising polymer sheets | 沙特基础全球技术有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-106068295-B | System and method for producing multiple molecular weight melt polycarbonates | 沙特基础工业全球技术有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-105408250-B | Method and apparatus for producing high-purity phosgene | 沙特基础全球技术有限公司 | 2018-08-07 | — | — | CN | disclosed |
| WO-2003050161-A1 | PROCESS FOR PREPARING BRANCHED AROMATIC POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2003-06-19 | — | — | WO | disclosed |
| US-20030060649-A1 | Solventless preparation of ester-substituted diaryl carbonates | GENERAL ELECTRIC COMPANY | 2003-03-27 | — | — | US | disclosed |
| WO-2003010218-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| WO-2003010220-A1 | EXTRUSION METHOD FOR MAKING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| WO-2003010123-A1 | SOLVENTLESS PREPARATION OF ESTER-SUBSTITUTED DIARYL CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |
| US-6506871-B1 | Ester interchange of bis(methyl salicyl) carbonate and bisphenol A in presence of tetrabutylphosphonium acetate catalyst | GENERAL ELECTRIC COMPANY | 2003-01-14 | — | — | US | disclosed |
| US-6437083-B1 | HAVING HIGH MELTING STRENGTHS IN A CONTINUOUS MELT REACTION SYSTEM; PHENOLIC BRANCHING AGENT | GENERAL ELECTRIC COMPANY | 2002-08-20 | — | — | US | disclosed |
| WO-2002053623-A2 | PROCESS FOR THE PRODUCTION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060649-A1 | Solventless preparation of ester-substituted diaryl carbonates | CDS2, ASH2L, PGGT1B | HPGD 1077/4885ALDH1A1 4720/4885KMT2A 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.