Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026590 | 0.83 | MAPT (0.45) | KDM4ENPC1MAPTSTAT3RAB9A | |
| SCHEMBL31026575 | 0.83 | MAPT (0.45) | KDM4ENPC1MAPTSTAT3RAB9A | |
| SCHEMBL31026577 | 0.83 | MAPT (0.45) | KDM4ENPC1MAPTSTAT3RAB9A | |
| SCHEMBL4463430 | 0.82 | KDM4E (0.62) | KDM4EPARP1CHRM1ACHE | |
| SCHEMBL15886704 | 0.81 | L3MBTL1 (0.44) | KDM4ENPC1MAPTSTAT3RAB9A | |
| SCHEMBL345367 | 0.81 | PARP1 (0.55) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9814936 | 0.80 | KDM4E (0.60) | KDM4EPARP1CHRM1ACHE | |
| Hydrochloric Acid SCHEMBL9814926 | 0.80 | KDM4E (0.60) | KDM4EPARP1CHRM1ACHE | |
| SCHEMBL11686678 | 0.80 | TRPV1 (0.59) | KDM4ENPC1RAB9ATRPV1PTGS2 | |
| SCHEMBL31026591 | 0.80 | CCR1 (0.53) | KDM4ENPC1MAPTSTAT3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362339-B1 | ELECTROLUMINESCENCE | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-26 | — | — | US | claimed |
| EP-1218345-B1 | METHOD OF MAKING METAL 8-QUINOLINOLATO COMPLEXES | 3M INNOVATIVE PROPERTIES CO (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1218345-A1 | METHOD OF MAKING METAL 8-QUINOLINOLATO COMPLEXES | 3M Innovative Properties Company (US) | 2002-07-03 | — | — | EP | disclosed |
| US-20020040143-A1 | Method of making metal 8-quinolinolato complexes | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-04 | — | — | US | disclosed |
| US-6362339-B1 | ELECTROLUMINESCENCE | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-26 | — | — | US | disclosed |
| WO-2001025211-A1 | METHOD OF MAKING METAL 8-QUINOLINOLATO COMPLEXES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040143-A1 | Method of making metal 8-quinolinolato complexes | COQ8A, SDHA, LDHA | KDM4E 2278/4885NPC1 4268/4885MAPT 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.