Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4464649 | 0.79 | KMT2A (0.40) | TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL3401058 | 0.78 | KMT2A (0.53) | HSP90AA1MEN1KMT2A | |
| SCHEMBL7442310 | 0.78 | MEN1 (0.62) | GAACYP19A1TSHRHSD17B10MEN1 | |
| SCHEMBL7393515 | 0.77 | CDC7 (0.39) | GAAHSP90AA1HSP90B1TSHRMEN1 | |
| SCHEMBL7446567 | 0.76 | TRPM5 (0.51) | GAACYP19A1CYP11B1CYP11B2LOXL2 | |
| SCHEMBL8327597 | 0.76 | TSHR (0.41) | KCNJ1KCNH2GAACYP19A1CYP11B1 | |
| Bromide SCHEMBL29657458 | 0.75 | FDPS (0.47) | TSHRMEN1KMT2A | |
| SCHEMBL1474745 | 0.74 | TBXAS1 (0.49) | MEN1KMT2ATBXAS1 | |
| SCHEMBL14611686 | 0.74 | HMOX1 (0.56) | KCNH2MEN1KMT2A | |
| SCHEMBL1004267 | 0.73 | LOXL2 (0.64) | KCNJ1KCNH2CYP19A1CYP2A6LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088702-C | Disubstituted bicyclic heterocycles, their production and use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-08-07 | — | — | CN | disclosed |
| CN-1248251-A | Disubstituted bicyclic heterocycles, their production and use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-03-22 | — | — | CN | disclosed |
| EP-0966454-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998037075-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-08-27 | — | — | WO | disclosed |