SCHEMBL4465007

SCHEMBL4465007

NC(=O)CC[C@H](N)C(=O)OCCCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
KMT2A Q03164 1/20 0.48
NOD1 Q9Y239 1/20 0.38
DPP4 P27487 1/20 0.37
DPP8 Q6V1X1 1/20 0.37
DPP9 Q86TI2 1/20 0.37
QARS1 P47897 1/20 0.33
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GSR P00390 1/20 0.32
CYP1A2 P05177 1/20 0.32
GRIK1 P39086 1/20 0.32
GRM5 P41594 1/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398286 0.89 ALOX15 (0.52) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL27914542 0.85 GRM8 (0.50) BLMKMT2ANOD1DPP4DPP8
SCHEMBL2323388 0.85 NOD1 (0.38) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL8009500 0.84 ALOX15 (0.56) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL28364075 0.84 ALOX15 (0.47) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL27956720 0.84 NOD1 (0.49) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL8581073 0.84 NOD1 (0.49) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL8749113 0.84 NOD1 (0.49) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL2732561 0.82 NOD1 (0.54) ALOX15BLMPMP22KMT2ANOD1
SCHEMBL6428430 0.82 ALOX15 (0.46) ALOX15BLMPMP22KMT2ANOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018156514-A1 PROCESSES FOR MAKING POLYISOBUTYLENE COMPOSITIONS NTP TEC, LLC (US) 2018-08-30 WO claimed
EP-1578450-A4 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRAL (AU) 2009-06-17 EP claimed
US-20060127310-A1 Amplification of biotin-mediated targeting ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD. 2006-06-15 US claimed
EP-1578450-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING Access Pharmaceuticals Australia Pty Ltd (AU) 2005-09-28 EP claimed
EP-1206252-A4 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING POLYMERS ACCESS PHARMACEUTICALS AUSTRAL (AU) 2005-02-16 EP claimed
WO-2004045647-A1 AMPLIFICATION OF BIOTIN-MEDIATED TARGETING ACCESS PHARMACEUTICALS AUSTRALIA PTY LTD (AU) 2004-06-03 WO claimed
EP-0701448-B1 AMPLIFICATION OF THE VITAMIN B 12 UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY LTD (AU) 2002-08-14 EP claimed
EP-1206252-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING POLYMERS BIOTECH AUSTRALIA PTY. LIMITED (AU) 2002-05-22 EP claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP claimed
WO-2000066091-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING POLYMERS BIOTECH AUSTRALIA PTY LIMITED (AU) 2000-11-09 WO claimed
EP-0700295-A4 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY LTD (AU) 1998-09-30 EP claimed
EP-0701448-A4 AMPLIFICATION OF THE VITAMIN B 12? UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY LTD (AU) 1997-01-02 EP claimed
US-5548064-A COLONY STIMULATING FACTOR; ORAL ADMINISTERING BIOTECH AUSTRALIA PTY LIMITED (AU) 1996-08-20 US claimed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
CN-1126436-A Vitamin B12 mediated oral delivery systems for GCSF and EPO BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
EP-0701448-A1 AMPLIFICATION OF THE VITAMIN B 12? UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY. LIMITED (AU) 1996-03-20 EP claimed
EP-0700295-A1 VITAMIN B 12? MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1996-03-13 EP claimed
US-5449720-A Amplification of the VB12 uptake system using polymers BIOTECH AUSTRALIA PTY LIMITED (AU) 1995-09-12 US claimed
WO-1994027641-A1 AMPLIFICATION OF THE VITAMIN B12 UPTAKE SYSTEM USING POLYMERS BIOTECH AUSTRALIA PTY. LIMITED (AU) 1994-12-08 WO claimed
WO-1994027613-A1 VITAMIN B12 MEDIATED ORAL DELIVERY SYSTEMS FOR GCSF AND EPO BIOTECH AUSTRALIA PTY. LIMITED (AU) 1994-12-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060127310-A1 Amplification of biotin-mediated targeting BTD, HLCS, SLC1A5 ALOX15 3126/4885BLM 4511/4885PMP22 1858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.