Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465007 | 0.89 | ALOX15 (0.48) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL8009500 | 0.88 | ALOX15 (0.56) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL5424018 | 0.84 | GRM8 (0.54) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL7541045 | 0.84 | MGLL (0.36) | ALOX15BLMPMP22KMT2AGRM8 | |
| SCHEMBL5424016 | 0.84 | MGLL (0.36) | ALOX15BLMPMP22KMT2AGRM8 | |
| SCHEMBL8998302 | 0.83 | TSHR (0.38) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL2305262 | 0.82 | ALOX15 (0.50) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL28643800 | 0.82 | KMT2A (0.50) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL8581073 | 0.79 | NOD1 (0.49) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL8749113 | 0.79 | NOD1 (0.49) | ALOX15BLMPMP22KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118680883-A | Loadable porous structure for use as an implant | 瑞艾克斯制药公司 | 2024-09-24 | — | — | CN | claimed |
| US-8354455-B2 | Prodrugs containing novel bio-cleavable linkers | Piramal Enterprises Limited and Apparao Satyam (IN) | 2013-01-15 | — | — | US | claimed |
| WO-2013004716-A1 | PEPTIDE BEADS | UNIVERSITÄT BASEL (CH) | 2013-01-10 | — | — | WO | claimed |
| US-20110274695-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | PIRAMAL LIFE SCIENCES LIMITED | 2011-11-10 | — | — | US | claimed |
| EP-2266625-A2 | Prodrugs Containing Novel Bio-Cleavable Linkers | Piramal Life Sciences Limited (IN) | 2010-12-29 | — | — | EP | claimed |
| US-20100081710-A1 | Modified L-Nucleic Acid | NOXXON PHARMA AG (DE) | 2010-04-01 | — | — | US | claimed |
| EP-2075011-A2 | Prodrugs Containing Bio-Cleavable Linkers | Piramal Life Sciences Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| JP-2008510795-A | — | — | 2008-04-10 | — | — | JP | claimed |
| US-20070196275-A1 | Diagnostic Imaging Compositions, Their Methods Of Synthesis And Use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-08-23 | — | — | US | claimed |
| EP-1789091-A2 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | Nicholas Piramal India Limited (IN) | 2007-05-30 | — | — | EP | claimed |
| EP-1389090-A2 | DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE | Board of Regents, The University of Texas System (US) | 2004-02-18 | — | — | EP | claimed |
| US-20030073615-A1 | Water soluble paclitaxel derivatives | CELL THERAPEUTICS, INC. | 2003-04-17 | — | — | US | claimed |
| US-20030003048-A1 | Diagnostic imaging compositions, their methods of synthesis and use | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-02 | — | — | US | claimed |
| WO-2002087498-A2 | DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-11-07 | — | — | WO | claimed |
| EP-0932399-A4 | WATER SOLUBLE PACLITAXEL PRODRUGS | PG TXL CO LP (US) | 2002-10-24 | — | — | EP | claimed |
| US-20010034363-A1 | WATER SOLUBLE PACLITAXEL DERIVATIVES | PG-TXL COMPANY, L.P. | 2001-10-25 | — | — | US | claimed |
| JP-2000507930-A | — | — | 2000-06-27 | — | — | JP | claimed |
| US-5977163-A | Water soluble paclitaxel prodrugs | PG-TXL COMPANY, L. P. (US) | 1999-11-02 | — | — | US | claimed |
| EP-0932399-A1 | WATER SOLUBLE PACLITAXEL PRODRUGS | PG-TXL Company, L.P. (US) | 1999-08-04 | — | — | EP | claimed |
| WO-1997033552-A1 | WATER SOLUBLE PACLITAXEL PRODRUGS | PG-TXL COMPANY, L.P. (US) | 1997-09-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274695-A1 | PRODRUGS CONTAINING NOVEL BIO-CLEAVABLE LINKERS | SI, UGT1A1, CYP2B6 | ALOX15 1077/4885BLM 2982/4885PMP22 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.