SCHEMBL2007943

SCHEMBL2007943

CCC(c1ccccc1C(N)=O)[Si](OC)(OC)OC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.44
HTT P42858 1/20 0.42
PARP1 P09874 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 2/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
CHRM2 P08172 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADRA2A P08913 1/20 0.39
OPRK1 P41145 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KDM4E B2RXH2 4/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 3/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14890258 0.84 PARP1 (0.36) IRAK4HTTPARP1MEN1KMT2A
SCHEMBL10949674 0.82 RAB9A (0.44) HTTMAPTLMNACYP3A4SLC6A3
SCHEMBL1639304 0.80 TSHR (0.42) MEN1KMT2ALMNACYP3A4KDM4E
SCHEMBL21084625 0.79 MEN1 (0.40) HTTMEN1KMT2AMAPTLMNA
SCHEMBL8526511 0.77 TSHR (0.55) IRAK4HTTPARP1MEN1KMT2A
SCHEMBL1380696 0.77 TSHR (0.55) IRAK4HTTPARP1MEN1KMT2A
SCHEMBL2010382 0.76 NOS3 (0.40) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL8161387 0.76 ALDH1A1 (0.40) CYP3A4ALDH1A1TSHRHSD17B10SMN1; SMN2
SCHEMBL4465341 0.76 TSHR (0.58) LMNACYP3A4HTR2BKDM4EALDH1A1
SCHEMBL474162 0.75 KDM4E (0.45) IRAK4HTTPARP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1740152-B1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO LTD (KR) 2012-12-26 EP claimed
US-7964747-B2 Poly(silsesquioxane) spherical particle containing ultraviolet light-absorbing group and manufacturing method thereof Saimdang Cosmetics, Co., Ltd. (KR) 2011-06-21 US claimed
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof SAIMDANG COSMETICS CO., LTD. (KR) 2007-10-25 US claimed
EP-1740152-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF Saimdang Cosmetics Co., Ltd. (KR) 2007-01-10 EP claimed
WO-2005105028-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO., LTD. (KR) 2005-11-10 WO claimed
EP-1740152-B1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO LTD (KR) 2012-12-26 EP disclosed
US-7964747-B2 Poly(silsesquioxane) spherical particle containing ultraviolet light-absorbing group and manufacturing method thereof Saimdang Cosmetics, Co., Ltd. (KR) 2011-06-21 US disclosed
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof SAIMDANG COSMETICS CO., LTD. (KR) 2007-10-25 US disclosed
EP-1740152-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF Saimdang Cosmetics Co., Ltd. (KR) 2007-01-10 EP disclosed
WO-2005105028-A1 POLY(SILSESQUIOXANE) SPHERICAL PARTICLE CONTAINING ULTRAVIOLET LIGHT-ABSORBING GROUP AND MANUFACTURING METHOD THEREOF SAIMDANG COSMETICS CO., LTD. (KR) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249854-A1 Poly(Silsesquioxane) Spherical Particle Containing Ultraviolet Light-Absorbing Group and Manufacturing Method Thereof STS, PARG, SBDS IRAK4 4174/4885HTT 2902/4885PARP1 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.